Consultancy and commercial services
Equipment
The BMRC currently has the following equipment. We offer training in all the instrumentation listed. Customers can also book time on our equipment with or without technical assistance, which is charged at an hourly rate*.
| Equipment type | Description |
| Bacterial fermentor systems | Can be used for growing bacteria or yeast organisms in batch or continuous culture |
| ÄKTA automated protein purification system for purification at 4° | Fully automated computer controlled system for the purification of proteins, where temperature sensitivity is an issue |
| ÄKTA automated protein purification system for purification at room temperature | Fully automated computer controlled system for the purification of proteins |
| Biacore | Label-free interaction analysis used for pharmaceutical drug discovery, antibody characterisation, proteomics and immunogenicity studies |
| Electrophysiology suite | Automated system for patch clamp analysis of study of single or multiple ion channels in cells. |
| Environmental test chambers | Growth chambers with variable temperature, O2, CO2 and humidity settings |
| Flow cytometer (FACScalibur) | Used for cell analysis and sorting, with 2 laser/4 colour analysis system |
| GC | For separating and analysing compounds that can be vaporized without decomposition |
| GC-MS | For separating and analysing compounds, the mass spectrometer components allows for identification of target molecules |
| GC-MS with probe for solid analysis | Can be used for the separation and identification of compounds in a solid sample |
| ICP-MS | For ion quantitation of solutions down to ppb levels |
| ICP-OES | For ion quantitation of solutions down to ppm levels |
| Ion chromatography | For separation of ions and polar molecules based on their charge, useful for halogen ion analysis which is not possible using the ICP systems |
| LC-MS | For separating and analysis compounds, particular useful in aqueous solutions |
| Li-cor odyssey infra red imager | Near infrared fluorescence detection for western blot analysis and protein detection |
| Microscopy suite | Our microscopy suite contains and Olympus fluorescent microscope, and inverted fluorescent microscope and a laser scanning confocal microscope. Can be used to analyse a variety of stained tissue, cell or bacterial samples |
| NMR | To determine physical, chemical, electronic and structural information of molecules |
| Portrait 630 non contact matrix spotter | Fully automated non-contact, nozzle-free acoustic droplet ejection system optimised to deposit MALDI matrix and other reagents onto tissue sections and other samples for precision MALDI imaging mass spectrometry. |
| Q-Star | Mass spectrometer coupled to MALDI ion source which allows MALDI-MS/MS-MS profiling and imaging of molecules within the range of 0 to 3000 Da, from a variety of samples. |
| Qstar Pulsar 1 LC-MS/MS | Coupled to an electrospray ion source for seperation and characterisation of target molecules |
| Stepone Real time PCR machine | Measures amplification of DNA as it occurs, cycle by cycle, allowing for precise and quantitative measurements during the exponential phase of PCR. |
| Sun Collect matrix spotter | HPLC effluent touch-off spotter for MALDI target spotting |
| Synapt G2 MALDI MS | Combined QuanTof and enhanced High Definition MS technologies, gives high resolution exact mass MS/MS analysis capabilities |
| Tecan automated liquid handling robot with integrated fluorescent plate reader | As our system is linked to a plate reader, this system is particularly useful for automated processing of ELISA systems |
| Voyager DE-Pro MS | Coupled to MALDI ion source which allows MALDI-MS profiling and imaging of target molecules in the range of 0 to 300,000 Da |
| Xcise automated gel cutting system | For automated spot picking and purification from SDS-PAGE gels, can also be used to automatically spot purified peptides onto MALDI-MS plates |
*subject to assessment of user competency
