- Biomolecular Sciences Research Centre
Main research emphasis is in the field of organophosphorus chemistry, in particular that of phosphonium salts and related compounds. Current interests include the preparation of phosphonioalkyl derivatives of biologically active molecules, the phosphonioalkyl group facilitating the passage of the biologically active agent through cell membranes, and studies of the formation of biologically active surface-functionalised gold nanoparticles. The ability of the phosphonium cation to be involved in 'hypervalent' interactions with donor molecules is also being studied, providing models of reactive intermediates in enzyme-catalysed reactions of organophosphorus compounds.
DJIDJA, Marie-Claude, CLAUDE, Emmanuelle, SCRIVEN, Peter, ALLEN, David, CAROLAN, Vikki and CLENCH, Malcolm (2017). Antigen retrieval prior to on-tissue digestion of formalin-fixed paraffin-embedded tumour tissue sections yields oxidation of proline residues. Biochimica et biophysica acta, 1865 (7), 901-906.
CHEN, Yu-Su, ALLEN, David, CROSS, Neil A, PITAK, Mateusz B, TIZZARD, Graham J, COLES, Simon J and BRICKLEBANK, Neil (2017). Biological and structural studies of phosphonium 'masked thiolate' compounds. European Journal of Medicinal Chemistry, 125, 528-537.
NICHOL, Kenneth J. and ALLEN, David (2015). The medicinal chemistry of ibuprofen. In: RAINSFORD, K. D., (ed.) Ibuprofen: discovery, development and therapeutics. Oxford, John Wiley and Son Ltd, 22-50.
LALWANI, Nikhil, CHEN, Yu-Su, CROSS, Neil, BROOKE, Gemma, ALLEN, David W., REYNOLDS, Alan, OJEDA, Jesús, TIZZARD, Graham J., COLES, Simon J. and BRICKLEBANK, Neil (2015). Triphenylarsonium-functionalised gold nanoparticles : potential nanocarriers for intracellular therapeutics. Chemical Communications, 51 (19), 4109-4111.
JU-NAM, Y., ALLEN, D. W., GARDINER, P. H. E. and BRICKLEBANK, N. (2008). Omega-thioacetylalkylphosphonium salts: precursors for the preparation of phosphonium-functionalised gold nanoparticles. Journal of organometallic chemistry, 693 (23), 3504-3508.
JU-NAM, Y., BRICKLEBANK, N., ALLEN, D. W., GARDINER, P. H. E., LIGHT, M. E. and HURSTHOUSE, M. B. (2006). Phosphonioalkylthiosulfate zwitterions - new masked thiol ligands for the formation of cationic functionalised gold nanoparticles. Organic and biomolecular chemistry, 4 (23), p. 4345.
ALLEN, D. W., BERRIDGE, R., BRICKLEBANK, N., FORDER, S. D., PALACIO, F., COLES, S. J., HURSTHOUSE, M. B. and SKABARA, P. J. (2003). Structural and magnetic properties of a novel ferrocenyl-diiodine. Inorganic chemistry, 42 (13), p. 3975.
ALLEN, D. W., BERRIDGE, R., BRICKLEBANK, N., CERRADA, E., LIGHT, M. E., HURSTHOUSE, M. B., LAGUNA, M., MORENO, A. and SKABARA, P. J. (2002). A new family of sulfur-rich ligands based on the dmit system: synthesis and metal complexation of 4–4'-covalently bridged bis(2-thioxo-1,3-dithiol-5-thiolato) units. Journal of the Chemical Society, Dalton Transactions.
ALLEN, D. W., HAWKRIGG, J., TRACEY, S. M., RAY, A. K. and HASSAN, A. K. (1997). Synthesis and characterization of a novel semiconducting N-alkylpyridinium benzimidazolate betaine-TCNQ charge-transfer complex. Synthetic Metals, 87 (1), 89-91.
Share this page
Are you sure you want to cancel your place on Saturday 12 November?