Following his undergraduate studies at Sheffield Hallam University, and MSc courses in the universities of Leeds and Sheffield Hallam, he completed a DPhil in Microvascular Physiology at the University of Nottingham, joining Hallam in 2013. Markos has extensive experience in the design, development and implementation of lifestyle interventions aiming to improve physiological and clinical outcomes for pre-clinical and clinical populations. He currently leads Lifestyle, Exercise and Nutrition Improvement (LENI) Research Group.
Markos is a fellow of Higher Education Academy (having completed a PGCE in Higher Education) and a member of the Physiological Society. He is also the lead of the U.K. Chapter for the International Union of Angiology Youth Committee. He has been invited to present his work and chair symposia in many international conferences (such as the 28th World Congress of the International Union of Angiology in Beijing, China in 2018 and FEPS 2019 Meeting of the Federation of European Physiological Societies in Bologna, Italy), having also delivered invited seminars and workshops both in the UK and overseas.
His group is currently investigating the effect of lifestyle interventions in the cardiovascular function of clinical and healthy-but-older populations. For example, they have been exploring how exercise can improve endothelial function in patients with chronic venous insufficiency and venous ulceration and reverse the ageing-affected microcirculation in older populations (FISCU II; funded by NIHR – Research for Patient Benefit Programme) and the effect of e-cigarettes in the micro- and macro-vascular physiology of smokers (ISME-NRT; funded by Heart Research UK).
Of particular interest to Markos and his group is the exploration of the effects of regional (e.g., Nordic, Mediterranean) and novelty (e.g., vegan, kefir-based) diets in younger and older groups. This series of projects is being undertaken in collaboration with other U.K. (e.g., Universities of Lincoln and Sheffield) and European (e.g., Aristotle University of Thessaloniki, University of Lille) universities.
Markos is also quite passionate about the reduction of non-communicable diseases in Black, Asian and Ethnic Minority (BAME) populations, and is currently leading a network of distinguished academics, BAME organisations and public health organisations and city councils, aiming to address the disparities faced by this population. Finally, another area of interest for Markos, is the predictive role of heamatological markers in the disease-outcome of patients with rectal cancer as well as the effect of cancer disease in the patients’ cardiopulmonary and microcirculatory function.
Research of Markos and his team is primarily focused on the investigation the effect of lifestyle interventions in the cardiovascular function of clinical and high-risk populations. Current and recently-completed projects include:
a) exercise-based interventions (for people with Systemic Sclerosis - led by Dr Alexandros Mitropoulos; for women with Polycystic Ovary Syndrome – led by Miss Amie Woodward; for people with Venous Leg Ulcers – led by Dr Klonizakis and managed by Miss McIntosh; for older people using aquatic-based exercise regimes – managed by Miss Hunt)
b) regional and novelty diet-based interventions (e.g., kefir-based diet, Mediterranean diet, New Nordic diet, vegan diet and green tea)
c) smoking cessation (involving the assessment of cardiovascular effects of electronic cigarettes for people making a stop smoking attempt).
Recently-funded research projects in which Markos collaborated and led include:
• “Exploring the feasibility of implementing a home-based exercise training and compression hosiery intervention in patients with venous ulceration (FISCU-II)” (funded by the NIHR-RfPB programme).
• “Impact on Cardiovascular Function in Smokers Making a Quit Attempt Using E-cigarettes Compared with Smokers Making a Quit Attempt with Prescription Nicotine Replacement Therapy (ISME-NRT)” (funded by Heart Research UK – Translational Grant). • "Stealth Marketing: Promoting Environmental Sustainability in the Workplace to Increase Employees’ Physical Activity" – (funded by Cancer Research UK Population Research Committee - BUPA Foundation Fund - Innovation Grant).
• "The Waiting Game: Promoting Physical Activity and Cancer Prevention at Public Bus Stops" – (funded by Cancer Research UK Population Research Committee - BUPA Foundation Fund - Innovation Grant).
• “Exploring the Feasibility of Implementing a Supervised Exercise Training and Compression Hosiery Intervention in Patients with Venous Ulceration (FISCU)” (funded by the NIHR-RfPB programme). Markos has collaborated extensively with academics and NHS healthcare professionals. Previous and current collaborations in the academic sector include King’s College London, Brunel University and Universities of Newcastle, Northumbria, Stirling, Sheffield, Nottingham and Lincoln (in the UK), Alabama (USA), Athens and Thessaloniki (Greece), Angiers (France), Lille (France), Plovdiv (Bulgaria) and Frankfurt (Germany). As far as the healthcare sector, he has worked in partnership with the Southern Derbyshire Acute Hospitals NHS Trust, the Sheffield NHS Hospitals Trust, the Leicester Teaching Hospitals NHS Trust, the East and North Herftordshire NHS Trust and the Hillingdon Hospitals NHS Foundation Trust amongst others.
Galan-Lopez, P., Domínguez, R., Gísladóttir, T., Sánchez-Oliver, A.J., Pihu, M., Ries, F., & Klonizakis, M. (2021). Sleep Quality and Duration in European Adolescents (The AdolesHealth Study): A Cross-Sectional, Quantitative Study. Children, 8 (3). http://doi.org/10.3390/children8030188
Jull, A., Wadham, A., Bullen, C., Parag, V., Parsons, J.G.M., Laking, G., ... O'Brien, J. (2021). Prescribed exercise regimen versus usual care and hypochlorous acid wound solution versus placebo for treating venous leg ulcers: study protocol for a randomised controlled trial (Factorial4VLU). BMJ Open, 11 (2), e043420. http://doi.org/10.1136/bmjopen-2020-043420
Manika, D., Blokland, Y., Smith, L., Mansfield, L., & Klonizakis, M. (2021). Using stealth marketing techniques to increase physical activity and decrease sedentary time in the workplace: A feasibility study investigating the spill-overs of employee pro-environmental behaviour. International Journal of Business Science and Applied Management, 16 (1), 28-49.
Klonizakis, M., Hunt, B.E., & Woodward, A. (2020). The association between cardiovascular function, measured as FMD and CVC, and long-term aquatic exercise in older adults (ACELA study): a cross-sectional study. Frontiers in Physiology, 11, 603435. http://doi.org/10.3389/fphys.2020.603435
Lenasi, H., Drenjancevic, I., & Klonizakis, M. (2020). Editorial: Exploration of the Physiological Effects of Exercise in Cardiovascular Diseases. Frontiers in Physiology, 11, 1097. http://doi.org/10.3389/fphys.2020.01097
Mitropoulos, A., Gumber, A., Crank, H., Akil, M., & Klonizakis, M. (2020). Exploring the feasibility of an exercise programme including aerobic and resistance training in people with limited cutaneous systemic sclerosis. Clinical Rheumatology, 39 (6), 1889-1898. http://doi.org/10.1007/s10067-019-04921-7
Woodward, A., Broom, D., Dalton, C., Metwally, M., & Klonizakis, M. (2020). Supervised exercise training and increased physical activity to reduce cardiovascular disease risk in women with polycystic ovary syndrome: Study protocol for a randomized controlled feasibility trial. Trials, 21 (1), 101. http://doi.org/10.1186/s13063-019-3962-7
Klonizakis, M., Grammatikopoulou, M.G., Theodoridis, X., Milner, M., Liu, Y., & Chourdakis, M. (2019). Effects of Long-Versus Short-Term Exposure to the Mediterranean Diet on Skin Microvascular Function and Quality of Life of Healthy Adults in Greece and the UK. Nutrients, 11 (10), e2487. http://doi.org/10.3390/nu11102487
Kesterton, S., Crank, H., Tew, G., Michaels, J., Gumber, A., McIntosh, E., ... Klonizakis, M. (2019). Participant experiences in a feasibility trial of supervised exercise training in adults with venous leg ulcers: a qualitative study. International Wound Journal. http://doi.org/10.1111/iwj.13252
Woodward, A., Broom, D., Harrop, D., Lahart, I., Carter, A., Dalton, C., ... Klonizakis, M. (2019). The effects of physical exercise on cardiometabolic outcomes in women with polycystic ovary syndrome not taking the oral contraceptive pill: a systematic review and meta-analysis. Journal of Diabetes & Metabolic Disorders, 18 (2), 597-612. http://doi.org/10.1007/s40200-019-00425-y
Mitropoulos, A., Gumber, A., Akil, M., & Klonizakis, M. (2019). Exploring the microcirculatory effects of an exercise programme including aerobic and resistance training in people with limited cutaneous systemic sclerosis. Microvascular Research, 125. http://doi.org/10.1016/j.mvr.2019.103887
Woodward, A., Klonizakis, M., Lahart, I., Carter, A., Dalton, C., Metwally, M., & Broom, D. (2019). The effects of exercise on cardiometabolic outcomes in women with polycystic ovary syndrome not taking the oral contraceptive pill: protocol for a systematic review and meta-analysis. Systematic Reviews, 8 (1). http://doi.org/10.1186/s13643-019-1030-8
Klonizakis, M. (2019). The Role of Microcirculatory Dysfunction in the Pathophysiology and Treatment of Venous Leg Ulcers. JAMA Dermatology, 155 (7), 861-862. https://jamanetwork.com/journals/jamadermatology/article-abstract/2732681
Theodoridis, X., Grammatikopoulou, M.G., Petalidou, A., Patelida, M., Gkiouras, K., Klonizakis, M., ... Bogdanos, D.P. (2019). Dietary management of celiac disease: revisiting the guidelines. Nutrition. http://doi.org/10.1016/j.nut.2019.04.008
Rogerson, D., Maçãs, D., Milner, M., Liu, Y., & Klonizakis, M. (2018). Contrasting effects of short-term mediterranean and vegan diets on microvascular function and cholesterol in younger adults: A comparative pilot study. Nutrients, 10 (12), 1897. http://doi.org/10.3390/nu10121897
Mitropoulos, A., Gumber, A., Crank, H., Akil, M., & Klonizakis, M. (2018). Investigating the effectiveness and feasibility of exercise on microvascular reactivity and quality of life in systemic sclerosis patients: study protocol for a feasibility study. Trials, 19, 647. http://doi.org/10.1186/s13063-018-2980-1
Liu, Y., Milner, M., & Klonizakis, M. (2018). Physiological effects of a short-term, lifestyle intervention based on the Mediterranean diet - comparison between older and younger healthy, sedentary adults. Nutrition, 55-56, 185-191. http://doi.org/10.1016/j.nut.2018.05.006
Klonizakis, M., Gumber, A., Mcintosh, E., King, B., Middleton, G., Michaels, J.A., & Tew, G. (2018). Exercise fidelity and progression in a supervised exercise programme for adults with venous leg ulcers. International Wound Journal, 15 (5), 822-828. http://doi.org/10.1111/iwj.12933
Klonizakis, M., Bianchi, S.M., Gernigon, M., Abraham, P., & Nawaz, S. (2018). Real-life adaptations in walking patterns in patients with established peripheral arterial disease assessed using a global positioning system in the community: A cohort study. Clinical Physiology and Functional Imaging, 38 (5), 889-894. http://doi.org/10.1111/cpf.12501
Klonizakis, M., Alkhatib, A., & Middleton, G. (2018). Commentary on: "Implementing a Mediterranean-Style Diet Outside the Mediterranean Region". Current atherosclerosis reports, 20 (9), 45. http://doi.org/10.1007/s11883-018-0744-8
Mitropoulos, A., Gumber, A., Crank, H., Akil, M., & Klonizakis, M. (2018). The effects of upper and lower limb exercise on the microvascular reactivity in limited cutaneous systemic sclerosis patients. ARTHRITIS RESEARCH & THERAPY, 20. http://doi.org/10.1186/513075-018-1605-0
Klonizakis, M., Tew, G., Gumber, A., Crank, H., King, B., Middleton, G., & Michaels, J.A. (2018). Supervised exercise training as an adjunct therapy for venous leg ulcers: a randomised controlled feasibility trial. British Journal Of Dermatology, 178 (5), 1072-1082. http://doi.org/10.1111/bjd.16089
Rogerson, D., McNeill, S., Kononen, H., & Klonizakis, M. (2018). Encouraging effects of a short-term, adapted Nordic diet intervention on skin microvascular function and skin oxygen tension in younger and older adults. Nutrition, 49, 96-101. http://doi.org/10.1016/j.nut.2017.11.001
Klonizakis, M., Tew, G.A., Gumber, A., Crank, H., King, B., Middleton, G., & Michaels, J.A. (2018). Supervised exercise training as an adjunct therapy for venous leg ulcers: a randomized controlled feasibility trial. British Journal of Dermatology, 178 (5), e361. http://doi.org/10.1111/bjd.16618
Tew, G.A., Gumber, A., Mcintosh, E., Kesterton, S., King, B., Michaels, J.A., & Klonizakis, M. (2017). Effects of supervised exercise training on lower-limb cutaneous microvascular reactivity in adults with venous ulcers. European Journal of Applied Physiology, 118 (2), 321-329. http://doi.org/10.1007/s00421-017-3772-0
Mitropoulos, A., Gumber, A., Crank, H., & Klonizakis, M. (2017). Validation of an arm crank ergometer test for use in sedentary adults. Journal of Sports Science and Medicine, 16, 558-564. http://www.jssm.org/abstresearchajssm-16-558.xml.xml
Oggioni, C., Jakovljevic, D.G., Klonizakis, M., Ashor, A.W., Ruddock, A., Ranchordas, M., ... Siervo, M. (2017). Dietary nitrate does not modify blood pressure and cardiac output at rest and during exercise in older adults : a randomised cross over study. International Journal of Food Sciences and Nutrition, 69 (1), 74-83. http://doi.org/10.1080/09637486.2017.1328666
Klonizakis, M., Crank, H., Gumber, A., & Brose, L.S. (2017). Smokers making a quit attempt using e-cigarettes with or without nicotine or prescription nicotine replacement therapy : impact on cardiovascular function (ISME-NRT) - a study protocol. BMC public health, 17 (1). http://doi.org/10.1186/s12889-017-4206-y
Hodges, G.J., Mallette, M.M., Tew, G.A., Saxton, J.M., Moss, J., Ruddock, A.D., & Klonizakis, M. (2017). Effect of age on cutaneous vasomotor responses during local skin heating. Microvascular Research, 112, 47-52. http://doi.org/10.1016/j.mvr.2017.03.002
Lenasi, H., & Klonizakis, M. (2017). Assessing the evidence: exploring the effects of exercise on diabetic microcirculation. Clinical Hemorheology and Microcirculation, 64 (4), 663-678. http://doi.org/10.3233/CH-168022
Siervo, M., Oggioni, C., Gjakovljevic, D.G., Trenell, M., Mathers, J.C., Houghton, D., ... Williams, E.A. (2016). Dietary nitrate does not have an effect on physical activity outcomes in healthy older adults : a randomized, cross-over trial. Nutrition Research, 36 (12), 1361-1369. http://doi.org/10.1016/j.nutres.2016.11.004
Wasilewski, R., Ubara, E.O., & Klonizakis, M. (2016). Assessing the effects of a short-term green tea intervention in skin microvascular and oxygen tension in older and younger adults. Microvascular Research, 107, 65-71. http://doi.org/10.1016/j.mvr.2016.05.001
Tew, G.A., Michaels, J., Crank, H., Middleton, G., Gumber, A., & Klonizakis, M. (2015). Supervised exercise training as an adjunctive therapy for venous leg ulcers: study protocol for a randomised controlled trial. Trials, 16 (1). http://doi.org/10.1186/s13063-015-0963-z
Humeau-Heurtier, A., & Klonizakis, M. (2015). Processing of laser Doppler Flowmetry signals from healthy subjects and patients with varicose veins : information categorization approach based on intrinsic mode functions and entropy computation. Medical Engineering and Physics, 37 (6), 553-559. http://doi.org/10.1016/j.medengphy.2015.03.020
Middleton, G., Keegan, R., Alkhatib, A., Smith, M., & Klonizakis, M. (2015). Implementing a Mediterranean diet intervention into a RCT : lessons learned from a non-Mediterranean based country, today. Journal of Nutrition, Health and Aging, 19 (7), 771-777. http://doi.org/10.1007/s12603-015-0663-0
Cogate, P.G., Natali, A.J., de Oliveira, A., Alfenas, R.C., & Hermsdorff, H.H.M. (2015). Consumption of Branched-Chain Amino Acids Is Inversely Associated with Central Obesity and Cardiometabolic Features in a Population of Brazilian Middle-Aged Men: Potential Role of Leucine Intake. J Nutr Health Aging, 19 (7), 771-777. http://doi.org/10.1007/s12603-015-0521-0
Klonizakis, M., Alkhatib, A., & Middleton, G. (2014). Long-term effects of an exercise and Mediterranean diet intervention in the vascular function of an older, healthy population. Microvascular Research, 95, 103-107. http://doi.org/10.1016/j.mvr.2014.07.015
Alkhatib, A., & Klonizakis, M. (2014). Effects of exercise training andMediterranean diet on vascular risk reductionin post-menopausal women. Clinical Hemorheology and Microcirculation, 57 (1), 33-47. http://doi.org/10.3233/CH-131770
Klonizakis, M., Moss, J., Gilbert, S., Broom, D., Foster, J., & Tew, G.A. (2014). Low-volume high-intensity interval training rapidly improvescardiopulmonary function in postmenopausal women. Menopause, 21 (10), 1099-1105. http://doi.org/10.1097/gme.0000000000000208
Klonizakis, M., Manning, G., Lingam, K., Donnelly, R., & Yeung, J.M.C. (2014). Effect of diabetes on the cutaneous microcirculation of the feet in patients with intermittent claudication. Clinical Hemorheology and Microcirculation, 61 (3), 439-444. http://doi.org/10.3233/CH-141907
Klonizakis, M., & Humeau-Heurtier, A. (2013). Multifractal analysis of laser Doppler flowmetry signals before and after arm-cranking exercise in an older healthy population. Journal of Medical Physics, 40 (2). http://doi.org/10.1118/1.4774362
Klonizakis, M., Alkhatib, A., Middleton, G., & Smith, M.F. (2013). Mediterranean diet- and exercise-induced improvement in age-dependent vascular activity. Clinical Science, 124 (9), 579-587. http://doi.org/10.1042/CS20120412
Khan, A.A., Klonizakis, M., Shabaan, A., & Glynne-Jones, R. (2013). Association between pretreatment haemoglobin levels and morphometric characteristics of the tumour, response to neoadjuvant treatment and long-term outcomes in patients with locally advanced rectal cancers. Colorectal Disease, 15 (10), 1232-1237. http://doi.org/10.1111/codi.12307
Klonizakis, M. (2012). Studying the cutaneous microcirculatory response during upper-limb exercise in healthy, older, sedentary people. Clinical Hemorheology and Microcirculation, 51 (1), 69-75. http://doi.org/10.3233/CH-2011-1510
Huedo-Medina, T.B., Kirsch, I., Middlemass, J., Klonizakis, M., & Siriwardena, A.N. (2012). Effectiveness of non-benzodiazepine hypnotics in treatment of adult insomnia: meta-analysis of data submitted to the Food and Drug Administration. British Medical Journal (BMJ), 17 (345). http://doi.org/10.1136/bmj.e8343
Klonizakis, M., Manning, G., & Donnelly, R. (2011). Assessment of lower limb microcirculation: exploring the reproducibility and clinical application of laser Doppler techniques. Skin Pharmacology and Physiology, 24 (3), 136-143. http://doi.org/10.1159/000322853
Klonizakis, M., Lingam, K., Manning, G., & Donnelly, R. (2011). Characterising the time-course of microvascular vasodilator responses in humans using Laser Doppler Fluximetry and iontophoresis. Journal of Pharmacological and Toxicological Methods, 63 (1), 115-118. http://doi.org/10.1016/j.vascn.2010.07.001
Tew, G., Klonizakis, M., Crank, H., Briers, J.D., & Hodges, G.J. (2011). Comparison of laser speckle contrast imaging with laser Doppler for assessing microvascular function. Microvascular Research, 82 (3), 326-332. http://doi.org/10.1016/j.mvr.2011.07.007
Yeung, J.M.C., Klonizakis, M., Lingam, K., Manning, G., & Donnelly, R. (2011). Effects of Lower Limb Angioplasty on Endothelial-Dependent and -Independent Microvascular Reactivity. European Journal of Vascular and Endovascular Surgery, 42 (6), 856. http://doi.org/10.1016/j.ejvs.2011.09.001
Klonizakis, M., & Winter, E. (2011). Effects of arm-cranking exercise in cutaneous microcirculation in older, sedentary people. Microvascular Research, 81 (3), 331-336. http://doi.org/10.1016/j.mvr.2011.01.008
Tew, G.A., Saxton, J.M., Klonizakis, M., Moss, J., Ruddock, A.D., & Hodges, G.J. (2011). Aging and aerobic fitness affect the contribution of noradrenergic sympathetic nerves to the rapid cutaneous vasodilator response to local heating. Journal of Applied Physiology, 110 (5), 1264-1270. http://doi.org/10.1152/japplphysiol.01423.2010
Tew, G., Klonizakis, M., Moss, J., Ruddock, A., Saxton, J., & Hodges, G.J. (2011). Role of sensory nerves in the rapid cutaneous vasodilator response to local heating in young and older endurance-trained and untrained men. Experimental Physiology, 96 (2), 163-170. http://doi.org/10.1113/expphysiol.2010.055434
Yeung, J.M.C., Klonizakis, M., Lingam, K., Manning, G., & Donnelly, R. (2011). Effects of lower limb angioplasty on endothelial-dependent and -independent microvascular reactivity. EJVES Extra, 22 (5). http://doi.org/10.1016/j.ejvsextra.2011.08.001
Tew, G., Klonizakis, M., & Saxton, J. (2010). Effects of ageing and fitness on skin-microvessel vasodilator function in humans. European journal of applied physiology, 109 (2), 173-181. http://doi.org/10.1007/s00421-009-1342-9
Klonizakis, M., Tew, G., Michaels, J.A., & Saxton, J. (2010). Effects of upper-limb exercise on lower-limb cutaneous microvascular function in post-surgical varicose-vein patients. European journal of applied physiology, 109 (6), 1221-1224. http://doi.org/10.1007/s00421-010-1471-1
Tew, G., Klonizakis, M., Moss, J., Ruddock, A., Saxton, J., & Hodges, G.J. (2010). Reproducibility of cutaneous thermal hyperaemia assessed by laser Doppler flowmetry in young and older adults. Microvascular Research, 81 (2), 177-182. http://doi.org/10.1016/j.mvr.2010.12.001
Kerr, S.F., Klonizakis, M., & Glynne-Jones, R. (2010). Suppression of the postoperative neutrophil leucocytosis following neoadjuvant chemoradiotherapy for rectal cancer and implications for surgical morbidity. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 12 (6), 549-554. http://doi.org/10.1111/j.1463-1318.2009.01858.x
Klonizakis, M., Tew, G., Michaels, J., & Saxton, J. (2009). Exercise training improves cutaneous microvascular endothelial function in post-surgical varicose vein patients. Microvascular research, 78 (1), 67-70. http://doi.org/10.1016/j.mvr.2009.03.002
Klonizakis, M., Tew, G., Michaels, J., & Saxton, J.M. (2009). Impaired microvascular endothelial function is restored by acute lower-limb exercise in post-surgical varicose vein patients. Microvascular research, 77 (2), 158-162. http://doi.org/10.1016/j.mvr.2008.09.009
Klonizakis, M., Yeung, J.M.C., Lingam, K., Nash, J.R., Manning, G., & Donnelly, R. (2006). Contrasting effects of varicose vein surgery on endothelial-dependent and -independent cutaneous vasodilation in the Perimalleolar Region. European Journal of Vascular and Endovascular Surgery, 31 (4), 434-438. http://doi.org/10.1016/j.ejvs.2005.10.017
Klonizakis, M. (2006). The Use of Magnetic Resonance Imaging in Cardiovascular Studies: A Case Study for Mitral Regurgitation. WSEAS Trans Maths Comp in Biol and Med, 3 (2), 311-316.
Klonizakis, M., Yeung, J.M.C., Nash, J.R., Lingam, K., Manning, G., & Donnelly, R. (2003). Effects of posture and venous insufficiency on endothelial-dependent and -independent cutaneous vasodilation in the perimalleolar region. European Journal of Vascular and Endovascular Surgery, 26 (1), 100-104. http://doi.org/10.1053/ejvs.2002.1953
Yeung, J.M.C., Klonizakis, M., Nash, J.R., Lingam, M.K., Manning, G., & Donnelly, R. (2002). Upright Posture Impairs Microvascular Vasodilation in Patients with Varicose Veins – Possible Role in Ulcer Formation. Clinical Science, 103 (s47), 7P-8P. http://doi.org/10.1042/cs103007pb
Cocate, P.G., Natali, A.J., de Oliveira, A., Alfenas, R.C., & Hermsdorff, H.H.M. (n.d.). Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of Brazilian middle-aged men: Potential role of leucine intake. The journal of nutrition, health & aging. http://doi.org/10.1007/s12603-015-0522-z
Klonizakis, M., Rogerson, D., Milner, M., Kononen, H., McNeill, S., & Liu, Y. (2019). Exploring the short-term, physiological, micro-circulatory effects of regional diets in sedentary, older, adult populations [Abstract only]. Acta Physiologica, 227 (S718), 13. http://doi.org/10.1111/apha.13366
Klonizakis, M. (2018). Using exercise as an adjunct therapy in microcirculatory diseases – reporting the evidence on venous ulceration and systemic sclerosis. Vascular Investigation and Therapy.
Mitropoulos, A., Gumber, A., Crank, H., Akil, M., & Klonizakis, M. (2018). The effects of upper and lower limb exercise on the microvascular reactivity in systemic sclerosis patients (abstract only). Annals of the Rheumatic Diseases, 77, 1788. http://doi.org/10.1136/annrheumdis-2018-eular.1979
Middleton, G., Keegan, R., Smith, M., Alkhatib, A., & Klonizakis, M. (2015). Exploring barriers and facilitators to eating the Mediterranean diet in England : a qualitative study. Proceedings of the Nutrition Society, 74 (OCE1). http://doi.org/10.1017/S0029665115001585
Klonizakis, M. (2015). INFLUENCE OF G6PD ON VASCULAR PHENOTYPE IN OBESE, OBESE-DIABETICS AND T2D. JOURNAL OF VASCULAR RESEARCH, 52, 21.
Hussain, F.H., Klonizakis, M., Ayube, J., Zaman, Q., & Khan, A. (2015). The Current Era Of Merging NHS Trusts - Impact on Patient Experience and Satisfaction to Re-Organised Surgical Services. BRITISH JOURNAL OF SURGERY, 102, 250-251.
Alkhatib, A., & Klonizakis, M. (2013). Reduction in post-menopausal related vascular dysfunction through exercise and Mediterranean diet. PROCEEDINGS OF THE NUTRITION SOCIETY, 72 (OCE4), E300. http://doi.org/10.1017/S0029665113003273
Klonizakis, M. (2011). Effect of ageing and fitness on skin-micro-vessel vasodilator function in humans. JOURNAL OF VASCULAR RESEARCH, 48, 36.
Amrou, S., Khan, A., Klonizakis, M., Anyamene, N., Mawdsley, S., Denton, A., ... Glynnes-Jones, R. (2010). THE IMPACT OF PRE-TREATMENT HAEMOGLOBIN AND TUMOUR LENGTH ON DISEASE FREE SURVIVAL AND LOCAL RECURRENCE IN RECTAL CANCERS TREATED WITH PRE-OPERATIVE CHEMO-RADIOTHERAPY. ANNALS OF ONCOLOGY, 21, 59-60.
Sharma, S., Moffat, D., Christopoulous, C., Klonizakis, M., Wellstead, D., Farrington, K., & Gorog, D.A. (2010). Global thrombotic status predicts cardiovascular events in end-stage renal failure. EUROPEAN HEART JOURNAL, 31, 971.
Klonizakis, M., Lenasi, H., & Drenjančević, I. (Eds.). (2020). Exploration of the Physiological Effects of Exercise in Cardiovascular Diseases. Frontiers.
Klonizakis, M., Lenasi, H., & Drenjančević, I. (Eds.). (2020). Exploration of the Physiological Effects of Exercise in Cardiovascular Diseases. Frontiers.
Klonizakis, M. (2010). Cutaneous Microcirculation and Lower-Limb Venous Disease. (1st). Saarbrücken, Germany: Lambert Academic Publishing.
Theses / Dissertations
Mitropoulos, A. (2018). The Effects of Exercise on Vascular Physiologyin Systemic Sclerosis Patients. (Doctoral thesis). Supervised by Klonizakis, M. http://doi.org/10.7190/shu-thesis-00213
Klonizakis, M. (2021). Can swimming help prevent cardiovascular disease? [Newspaper Article]. https://www.independent.co.uk/health_and_wellbeing/swimming-water-exercise-pool-cardiovascular-disease-b1776190.html
Wardill, J. (2020). "15 weeks of hell": A story of a Long-haul COVID-19 sufferer. [Newspaper Article].
Benz, M. (2020). Brief Mediterranean diet intervention may have long term benefits. [Journal article]. https://medicalresearch.com/author-interviews/brief_mediterranean_diet_intervention_may_have_long_term_benefits/8924/
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Markos is an editor in the Journal of Pharmacological and Toxicological Methods (since 2011), Clinical Hemorheology and Microcirculation (since 2014) and a guest editor for Frontiers of Physiology (since 2018). He has completed reviews for Microvascular Research, Journal of Pharmacological and Toxicological Methods, Skin Pharmacology and Physiology, Quality in Primary Care, Current Vascular Pharmacology, Acta Physiologica, Inflammation Research and Microcirculation.
He has also acted as an external moderator for the University of Wales between 2012-2016 and he is a currently an international advisor for the Factorial4VLU trial, a study targeting people with Venous Leg Ulcers, funded by the Health Research Council of New Zealand and hosted by the University of Auckland.
Markos is the Director of Studies for Miss Aime Woodward (who is exploring the effects of exercise on women with Polycystic Ovary Syndrome) and a 2nd supervisor for Mr Tom Parkington (who is exploring lower-body resistance exercise in people with Peripheral Arterial Disease). He has led the supervisory team for two MD and two PhD students in the past.
Markos has given provided expert opinions on the effects of pregnancy on exercise performance (BBC Sport, "The Washington Post" newspaper), on nutrition ("The Sun" newspaper) as well as on the physiological effects of smoking cessation ("Sheffield Star" newspaper, BBC Radio, Hallam FM). His articles on "The Conversation" have been reprinted in many national and international media, while he has written articles published in "The Independent" newspaper.
Recent work by Markos and his colleagues on the effects of the Mediterranean Diet in the vascular function of older, sedentary people has been featured in regional (Yorkshire and Lincolnshire), national and international (Greece, USA and Australia) media, with interviews being given to the "Fitness" magazine, medical research websites and blogs, and the BBC regional radio stations.