Neil was appointed to Sheffield Hallam having completed BSc Chemistry and a PhD in Inorganic Chemistry at UMIST (Manchester). He teaches inorganic and materials chemistry and has an active research group investigating the biological applications of inorganic nanomaterials.
He is a Senior Fellow of the Higher Education Academy, a Chartered Chemist and a Fellow of the Royal Society of Chemistry.
Neil Bricklebank is a chartered chemist working across the Department of Biosciences and Chemistry, where he is Professional Lead for Chemistry and Forensic Science, and the Biomolecular Sciences Research Centre.
Neil can demonstrate a sustained record of effectiveness in relation to teaching and learning, and led, the development and introduction of Chemistry degrees at Sheffield Hallam. He is a member of the standing committee of the UK Heads of Chemistry group and was appointed a Senior Fellow of the Higher Education Academy in 2013.
He believes passionately in public engagement and the importance of promoting science, especially chemistry, to children and young people, and regularly delivers lectures and hands-on workshops at both primary and secondary levels.
He has an international standing in the field of inorganic materials chemistry working at the interface of chemistry, nanomaterials and biological sciences, and currently leads a number of research projects including the synthesis and characterisation of functionalised nanoparticles for intra-cellular diagnostics and therapeutic, novel iodine-containing composites as wound healing materials He has considerable experience of knowledge-transfer and consultancy and has completed projects with local, national and multinational companies.
Before joining Sheffield Hallam Neil worked in the chemical industry and completed a BSc in Chemistry and a PhD in Inorganic Chemistry at UMIST (Manchester) , and post-doctoral research positions at UMIST and Durham Universities.
Plant Nutrients and Hydroponics
Plants require a range of inorganic ions and minerals, particularly phosphate, nitrate, potassium, and other metal ions, for strong and healthy growth and development. We are working to develop new and improved nutrients for use in hydroponic systems. Hydroponics, the growth of plants in soilless media, is an advanced horticultural technique that is used commercially across the world for growing fruit and vegetable crops. We are also using mass spectrometry to study the uptake and distribution of metal ions by plants.
Biomedical applications of phosphonium compounds
Organo phosphonium compounds are a family of lipophilic cations that are of interest because of their potential applications in biomedical science. We have developed a series of phosphonium zwitterions and salts that can be used to prepare cationically-functionalised nanoparticles. We are investigating the interaction of the phosphonium compounds and functionalised nanoparticles as agents for mitochondria-targeted diagnostics and therapeutics.
Polymer Nanocomposite materials
Composite materials composed of inorganic particles and ions embedded in natural or synthetic polymers have a host of applications ranging from electro-active species and catalysts to biomedical materials. We are investigating the synthesis of materials containing halogens, especially iodine, for application as antibacterial agents and wound healing.
Dr Jon Golding, Open University
Professor Alan Reynolds, Brunel University
Dr Jesus J. Ojeda, Swansea University
Industrial Collaborators include Aqualabs Ltd and Croda Europe.
Y. Ju-Nam, Y-S. Chen, J.J.Ojeda, D.W. Allen, N.A.Cross, P.H.E.Gardiner and N. Bricklebank, 'Water-soluble gold nanoparticles stabilized with cationic phosphonium thiolate ligands' RSC Advances, 2012, 2, 10345-10351. DOI: 10.1039/C2RA21421K. ISSN: 2046-2069
CHEN, Yu-Su, ALLEN, David, CROSS, Neil A, PITAK, Mateusz B, TIZZARD, Graham J, COLES, Simon J and BRICKLEBANK, Neil (2017). Biological and structural studies of phosphonium 'masked thiolate' compounds. European Journal of Medicinal Chemistry, 125, 528-537.
LALWANI, Nikhil, CHEN, Yu-Su, CROSS, Neil, BROOKE, Gemma, ALLEN, David W., REYNOLDS, Alan, OJEDA, Jesús, TIZZARD, Graham J., COLES, Simon J. and BRICKLEBANK, Neil (2015). Triphenylarsonium-functionalised gold nanoparticles : potential nanocarriers for intracellular therapeutics. Chemical Communications, 51 (19), 4109-4111.
LALWANI, Nikhil, CHEN, Yu-Su, BROOKE, Gemma, CROSS, Neil A., ALLEN, David W., REYNOLDS, Alan, OJEDA, Jesús, TIZZARD, Graham J., COLES, Simon J. and BRICKLEBANK, Neil (2015). Triphenylarsonium-functionalised gold nanoparticles: potential nanocarriers for intracellular therapeutics. Chemical Communications, 51 (19), 4109-4111.
SEAMAN, Callie, FLINDERS, Bryn, EIJKEL, Gert, HEEREN, Ron M.A., BRICKLEBANK, Neil and CLENCH, Malcolm R. (2014). “Afterlife Experiment”: use of MALDI-MS and SIMS imaging for the Study of the nitrogen cycle within plants. Analytical Chemistry, 86 (20), 10071-10077.
MANCINI, Annalisa, ARAGONI, M. Carla, BRICKLEBANK, Neil, CASTELLANO, Carlo, DEMARTIN, Francesco, ISAIA, Francesco, LIPPOLIS, Vito, PINTUS, Anna and ARCA, Massimiliano (2013). Formation of T-Shaped versus Charge-Transfer Molecular Adducts in the Reactions Between Bis(thiocarbonyl) Donors and Br2and I2. Chemistry : An Asian Journal, 8 (3), 639-647.
MANCINI, Annalisa, ARAGONI, M. Carla, BRICKLEBANK, Neil, CASTELLANO, Carlo, DEMARTIN, Francesco, ISAIA, Francesco, LIPPOLIS, Vito, PINTUS, Anna and ARCA, Massimiliano (2012). Formation of T-Shaped versus Charge-Transfer Molecular Adducts in the Reactions Between Bis(thiocarbonyl) Donors and Br2and I2. Chemistry - An Asian Journal, 8 (3), 639-647.
MANCINI, Annalisa, PALA, Luca, ARAGONI, M. Carla, ARCA, Massimiliano, DEVILLANOVA, Francesco A., HURSTHOUSE, Michael B., LIGHT, Mark E., SKABARA, Peter J. and BRICKLEBANK, Neil (2012). Structural and DFT Studies of Dibromine and Diiodine Adducts of a Sulfur-Rich Thiocarbonyl Donor. European Journal of Inorganic Chemistry, 2012 (14), 2373-2380.
JU-NAM, Y., ALLEN, D. W., GARDINER, P. H. E. and BRICKLEBANK, N. (2008). Omega-thioacetylalkylphosphonium salts: precursors for the preparation of phosphonium-functionalised gold nanoparticles. Journal of organometallic chemistry, 693 (23), 3504-3508.
JU-NAM, Y., BRICKLEBANK, N., ALLEN, D. W., GARDINER, P. H. E., LIGHT, M. E. and HURSTHOUSE, M. B. (2006). Phosphonioalkylthiosulfate zwitterions - new masked thiol ligands for the formation of cationic functionalised gold nanoparticles. Organic and biomolecular chemistry, 4 (23), p. 4345.
LEE, L., CROUCH, D. J., WRIGHT, S. P., BERRIDGE, R., SKABARA, P. J., BRICKLEBANK, N., COLES, S. J., LIGHT, M. E. and HURSTHOUSE, M. B. (2004). Supramolecular polymers of 4,5-bis(bromomethyl)-1,3-dithiole-2-thione-dihalogen adducts. CrystEngComm, 6, p. 612.
ALLEN, D. W., BERRIDGE, R., BRICKLEBANK, N., FORDER, S. D., PALACIO, F., COLES, S. J., HURSTHOUSE, M. B. and SKABARA, P. J. (2003). Structural and magnetic properties of a novel ferrocenyl-diiodine. Inorganic chemistry, 42 (13), p. 3975.
ALLEN, D. W., BERRIDGE, R., BRICKLEBANK, N., CERRADA, E., LIGHT, M. E., HURSTHOUSE, M. B., LAGUNA, M., MORENO, A. and SKABARA, P. J. (2002). A new family of sulfur-rich ligands based on the dmit system: synthesis and metal complexation of 4–4'-covalently bridged bis(2-thioxo-1,3-dithiol-5-thiolato) units. Journal of the Chemical Society, Dalton Transactions.
Member of the standing committee of the UK Heads of Chemistry group
Member of the EPSRC Peer Review College
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