Professor Charmaine Childs PhD
Professor of Clinical Science
Summary
My clinical research interest is in the field of human trauma. I have a significant track record in the field of systemic injury (burns) and neurological (brain) damage. My current research focus is on the development and implementation of novel, non-invasive clinical and imaging biomarkers as a forewarning of clinical deterioration originating from injuries which lead to wounds both ‘’inside’’ and ‘’outside’’ the body.
About
After qualifying, care of burned children inspired my research interests. I received National/International recognition winning a number of scientific prizes in paediatric trauma. Later, as an MRC scientist, I led the metabolic research programme on childhood burn trauma. Building a bespoke calorimeter to measure energy expenditure, our ‘metabolic-cart’ became the prototype for later commercial systems.
By 2000, injured brain became my research focus. Pioneering new, implantable, brain sensors, the objective was to forge new ways to reduce secondary brain damage. Results were controversial; challenging existing dogma, specifically on brain temperature.
In 2009, invited to the National University of Singapore, I explored new invasive and non-invasive imaging modalities for sepsis, brain-injury diagnosis and wound infection. Now back in the UK, my research programme combines my interests of non-invasive imaging diagnosis in trauma; the injured body (with a focus on surgical site infection) and, as we enter an era of brain injury awareness, the injured brain; specifically concussion in sport.
Within the Health and Social Care Research, I lead the Clinical and Imaging Biomarkers of Health and Disease (CIBoHD) theme.
Research Interests: TRAUMA and SURGERY
- Surgical site infection
- Severe traumatic brain injury and neurocritical care
- Concussion in sports
- Human thermoregulation: fever and brain cooling
- Prognostic performance of serum biomarkers
- Sepsis
IMAGING
Advanced, invasive multiparameter neuromonitoring (temperature, pressure and oxygen content)
Non-invasive Imaging
- Magnetic resonance spectroscopy (1HMRS) and imaging (1HMRSI)
- Non-invasive infra-red thermal imaging
- Optical coherence tomography (OCT) and retinal imaging.
Research
Publications
Key Publications
Childs, C., Sandy-Hodgetts, K., Broad, C., Cooper, R., Manresa, M., & Verdú-Soriano, J. (2020). Birth-related wounds. Journal of Wound Care, 29, 1-48.
Journal articles
Roscoe, S., Skinner, E., Kabucho Kibirige, E., Childs, C., Weekes,, C.E., Wootton, S., ... Stavroulakis, T. (2023). A critical view of the use of predictive energy equations for the identification of hypermetabolism in motor neuron disease : a pilot study. Clinical Nutrition ESPEN. http://doi.org/10.1016/j.clnesp.2023.08.017
Kirk, C., & Childs, C. (2023). Combat Sports as a Model for Measuring the Effects of Repeated Head Impacts on Autonomic Brain Function: A Brief Report of Pilot Data. Vision, 7 (2). http://doi.org/10.3390/vision7020039
Childs, C., Nwaizu, H., Bullivant, E., Willmott, J., Davies, M., Ousey, K., ... Jacques, R. (2023). Cutaneous perfusion dynamics of the lower abdomen in healthy normal weight, overweight and obese women: methods development using infrared thermography with applications for future wound management after caesarean section. International Journal of Environmental Research and Public Health, 20 (6). http://doi.org/10.3390/ijerph20065100
Usman, J.E., Childs, C., Rogerson, D., & Klonizakis, M. (2022). A systematic review of internet-based interventions for the prevention and self-management of cardiovascular diseases among people of African descent. International Journal of Environmental Research and Public Health, 19 (14). http://doi.org/10.3390/ijerph19148872
Usman, J.E., Childs, C., Rogerson, D., & Klonizakis, M. (2022). A systematic review of internet-based interventions for the prevention and self-management of cardiovascular diseases among people of African descent. International Journal of Environmental Research and Public Health, 19 (14). http://doi.org/10.3390/ijerph19148872
Tamang, P., Childs, C., Stephenson, J., & Ousey, K. (2022). Is there a place for surgical site assessment using new imaging modalities during routine clinical care? A review of dressings use and changes from an online survey. Wounds UK, 18 (2), 11-18. https://www.wounds-uk.com/journals/issue/660/article-details/there-place-surgical-site-assessment-using-new-imaging-modalities-during-routine-clinical-care-review-dressing-use-and-changes-online-survey
Yi, C.Y., Childs, C., Peng, C., & Robinson, D. (2021). Thermal comfort modelling of older people living in care homes: An evaluation of heat balance, adaptive comfort, and thermographic methods. Building and Environment. http://doi.org/10.1016/j.buildenv.2021.108550
Childs, C., Elliott, J., Khatab, K., Hampshaw, S., Fowler-Davis, S., Willmott, J., & Ali, A. (2020). Thermal Sensation in Older People, with and without Dementia, Living in Residential Care: New Assessment Approaches Using Infrared Thermography. . http://doi.org/10.20944/preprints202008.0337.v1
Childs, C., & Soltani, H. (2020). Abdominal cutaneous thermography and perfusion mapping after caesarean section: A scoping review. International Journal of Environmental Research and Public Health, 17 (22).
Childs, C., Elliott, J., Khatab, K., Hampshaw, S., Fowler-Davis, S., Willmott, J.R., & Ali, A. (2020). Thermal Sensation in Older People with and without Dementia Living in Residential Care: New Assessment Approaches to Thermal Comfort Using Infrared Thermography. International Journal of Environmental Research and Public Health — Open Access Journal, 17 (18), e6932. http://doi.org/10.3390/ijerph17186932
Saednia, K., Tabbarah, S., Lagree, A., Wu, T., Klein, J., Garcia, E., ... Tran, W. (2020). Thermoradiomic Markers of Radiation-Induces Skin Toxicity: Updated Results of a Phase II Study. Journal of Medical Imaging and Radiation Sciences, 51 (3), S3. http://doi.org/10.1016/j.jmir.2020.07.012
Saednia, K., Tabbarah, S., Lagree, A., Wu, T., Klein, J., Garcia, E., ... Tran, W. (2020). Quantitative thermal imaging biomarkers to detect acute skin toxicity from breast radiation therapy using supervised machine learning. International Journal of Radiation Oncology*Biology*Physics, 106 (5), 1071-1083. http://doi.org/10.1016/j.ijrobp.2019.12.032
Siah, C.J., Childs, C., Chia, C.K., & Cheng, K.-.F.K. (2019). An observational study of temperature and thermal images of surgical wounds for detecting delayed wound healing within four days after surgery. Journal of clinical nursing, 28 (11-12), 2285-2295. http://doi.org/10.1111/jocn.14832
Cleary, M., Raeburn, T., West, S., & Childs, C. (2019). The environmental temperature of the residential care home: role in thermal comfort and mental health? Contemporary nurse. http://doi.org/10.1080/10376178.2019.1583068
Childs, C., Wright, N., Willmott, J., Davies, M., Kilner, K., Ousey, K., ... Stephenson, J. (2019). The surgical wound in infrared: thermographic profiles and early stage test-accuracy to predict surgical site infection in obese women during the first 30 days after caesarean section. Antimicrobial resistance and infection control, 8 (7). http://doi.org/10.1186/s13756-018-0461-7
Childs, C., Barker, L.A., Gage, A.M.D., & Loosemore, M. (2018). Investigating possible retinal biomarkers ofhead trauma in Olympic boxers using opticalcoherence tomography. Eye and Brain, 10, 101-110. http://doi.org/10.2147/EB.S183042
Marshall, M., Deo, R., Childs, C., & Ali, A. (2018). Feasibility and Variability of Automated Pupillometry Among Stroke Patients and Healthy Participants: Potential Implications for Clinical Practice. The Journal of neuroscience nursing, 1. http://doi.org/10.1097/JNN.0000000000000416
Kornhaber, R., Childs, C., & Cleary, M. (2018). Experiences of guilt, shame and blame in those affected by burns trauma : a qualitative systematic review. Burns, 44 (5), 1026-1039. http://doi.org/10.1016/j.burns.2017.11.012
Tran, W.T., Childs, C., Probst, H., Farhat, G., & Czarnota, G.J. (2018). Imaging Biomarkers for Precision Medicine in Locally Advanced Breast Cancer. Journal of Medical Imaging and Radiation Sciences, 49 (4), 342-351. http://doi.org/10.1016/j.jmir.2017.09.006
Tran, W.T., Gangeh, M.J., Sannachi, L., Chin, L., Watkins, E., Bruni, S.G., ... Czarnota, G.J. (2017). Predicting Breast Cancer Response to Neoadjuvant Chemotherapy Using Pretreatment Diffuse Optical Spectroscopic-Texture Analysis. British journal of cancer, 116 (10), 1329-1339. http://doi.org/10.1038/bjc.2017.97
Childs, C., Siraj, M.R., Fair, F., Selvan, A., Soltani, H., Wilmott, J., & Farrell, R. (2016). Thermal territories of the abdomen after Caesarean Section birth : infrared thermography and analysis. Journal of wound care, 25 (9), 499-512. http://doi.org/10.12968/jowc.2016.25.9.499
Tran, W.T., Childs, C., Chin, L., Slodkowska, E., Sannachi, L., Tadayyon, H., ... Czarnota, G.J. (2016). Multiparametric monitoring of chemotherapy treatment response in locally advanced breast cancer using quantitative ultrasound and diffuse optical spectroscopy. Oncotarget, 7 (15), 19762-19780. http://doi.org/10.18632/oncotarget.7844
Siah, C.J.R., & Childs, C. (2015). Thermographic mapping of the abdomen in healthy subjects and patients after enterostoma. Journal of wound care, 24 (3), 112-120. http://doi.org/10.12968/jowc.2015.24.3.112
Childs, C., & Shen, L. (2015). Regional pressure and temperature differences across the injured human brain : comparisons between intraparenchymal and ventricular measurements. Critical Care, 19 (1), 267. http://doi.org/10.1186/s13054-015-0982-x
Lim, S.-.F., Ong, S.Y., Tan, Y.L., Ng, Y.S., Chan, Y.H., & Childs, C. (2015). Incidence and predictors of new-onset constipation during acute hospitalisation after stroke. International Journal of Clinical Practice, 69 (4), 422-428. http://doi.org/10.1111/ijcp.12528
Martínez-Morillo, E., Childs, C., García, B.P., Álvarez Menéndez, F.V., Romaschin, A.D., Cervellin, G., ... Diamandis, E.P. (2015). Neurofilament medium polypeptide (NFM) protein concentration is increased in CSF and serum samples from patients with brain injury. Clinical Chemistry and Laboratory Medicine, 53 (10), 1575-1584. http://doi.org/10.1515/cclm-2014-0908
Childs, C., Wang, L., Neoh, B.K., Goh, H.L., Zu, M.M., Aung, P.W., & Yeo, T.T. (2014). Multi-parameter brain tissue microsensor and interface systems : calibration, reliability and user experiences of pressure and temperature sensors in the setting of neurointensive care. Journal of Medical Engineering & Technology, 38 (7), 339-350. http://doi.org/10.3109/03091902.2014.937834
Lesko, M.M., O’Brien, S.J., Childs, C., Bouamra, O., Rainey, T., & Lecky, F. (2014). Comparison of several prognostic tools in traumatic brain injury including S100B. Brain Injury, 28 (7), 987-994. http://doi.org/10.3109/02699052.2014.890743
Yeeles, H., Trinick, S., Childs, C., Soltani, H., & Farrell, T. (2014). Postpartum infection in morbidly obese women after caesarean section : does early prophylactic oral antibiotic use make a difference? Open Journal of Obstetrics and Gynecology, 4 (9), 547-549. http://doi.org/10.4236/ojog.2014.49077
Childs, C., Ong, Y.T., Zu, M.M., Aung, P.W., Cheung, C.Y., & Kuan, W.S. (2014). Retinal imaging: a first report of the retinal microvasculature in acute mild traumatic brain injury. European Journal of Emergency Medicine, 21 (5), 388-389. http://doi.org/10.1097/MEJ.0000000000000169
Mattar, I., Chan, M.F., & Childs, C. (2013). Risk factors for acute delirium in critically ill adult patients: a systematic review. ISRN Critical Care, 2013. http://doi.org/10.5402/2013/910125
Childs, C., Liu, K., Vail, A., & Pan, J. (2013). Time-dependent relationships between human brain and body temperature after severe traumatic brain injury. International Journal of Statistics in Medical Research, 2 (1), 14-22. http://doi.org/10.6000/1929-6029.2013.02.01.02
Lesko, M.M., Jenks, T., Perel, P., O'Brien, S., Childs, C., Bouamra, O., & Lecky, F. (2013). Models of mortality probability in severe traumatic brain injury : results of the modelling by the UK Trauma Registry. Journal of Neurotrauma, 30 (24), 2021-2030. http://doi.org/10.1089/neu.2013.2988
Childs, C., Martínez-Morillo, E., Wai, A.P., Zu, M.M., Diamandis, A., & Diamandis, E.P. (2013). Exploring the relationship between serum biomarkers, acute intracerebral changes and outcome after severe traumatic brain injury (TBI). Clinical Chemistry and Laboratory Medicine, 51 (9), e195-e197. http://doi.org/10.1515/cclm-2013-0216
Lim, S.F., & Childs, C. (2013). A systematic review of the effectiveness of bowel management strategies for constipation in adults with stroke. International Journal of Nursing Studies, 50 (7), 1004-1010. http://doi.org/10.1016/j.ijnurstu.2012.12.002
Childs, C., & Lunn, K. (2013). Clinical review : brain-body temperature differences in adults with severe traumatic brain injury. Critical Care, 17 (2), 222. http://doi.org/10.1186/cc11892
Vescovo, E., Levick, A., Childs, C., Machin, G., Zhao, S., & Williams, S.R. (2013). High-precision calibration of MRS thermometry using validated temperature standards: effects of ionic strength and protein content on the calibration. NMR in Biomedicine, 26 (2), 213-223. http://doi.org/10.1002/nbm.2840
Lim, D.A.F.N., Chan, M., & Childs, C. (2013). Surrogate consent for critical care research: exploratory study on public perception and influences on recruitment. Critical Care, 17 (1), R5. http://doi.org/10.1186/cc11927
Lesko, M.M., Jenks, T., O'Brien, S.J., Childs, C., Bouamra, O., Woodford, M., & Lecky, F. (2013). Comparing model performance for survival prediction using total Glasgow Coma Scale and its components in traumatic brain injury. Journal of Neurotrauma, 30 (1), 17-22. http://doi.org/10.1089/neu.2012.2438
Childs, C., Zu, M.M., Wai, A.P., Tsai, Y.T., Wu, S., & Li, W. (2012). Infra-red thermal imaging of the inner canthus : correlates with the temperature of the injured human brain. Engineering, 4 (10B), 53-56. http://doi.org/10.4236/eng.2012.410B014
Childs, C., Wai, A.P., Zu, M.M., Nga, V.D.W., Sun, I.S., Kejia, T., ... Yeo, T.T. (2012). Mapping the incidence of focal tissue hypoxia after decompressive craniectomy. Brain Injury, 26 (9), 1163. http://doi.org/10.3109/02699052.2012.696431
Siah, C.J., & Childs, C. (2012). A systematic review of the ASEPSIS scoring system used in non-cardiac-related surgery. Journal of wound care, 21 (3), 124, 126-30.
Childs, C., Ng, A.L.C., Liu, K., & Pan, J. (2011). Exploring the sources of ‘missingness’ in brain tissue monitoring datasets: an observational cohort study. Brain Injury, 25 (12), 1163-1169. http://doi.org/10.3109/02699052.2011.607791
Lesko, M.M., Rainey, T., Childs, C., Bouamra, O., O’Brien, S., & Lecky, F. (2010). Comparing the prognostic performance of S100B with prognostic models in traumatic brain injury. Injury Extra, 41 (12), 156-157. http://doi.org/10.1016/j.injury.2010.07.472
Sacho, R.H., Vail, A., Rainey, T., King, A.T., & Childs, C. (2010). The effect of spontaneous alterations in brain temperature on outcome: a prospective observational cohort study in patients with severe traumatic brain injury. Journal of Neurotrauma, 27 (12), 2157-2164. http://doi.org/10.1089/neu.2010.1384
Childs, C., Wieloch, T., Lecky, F., Machin, G., Harris, B., & Stocchetti, N. (2010). Report of a consensus meeting on human brain temperature after severe traumatic brain injury : its measurement and management during pyrexia. Frontiers in Neurology, 1 (146). http://doi.org/10.3389/fneur.2010.00146
Childs, C. (2010). Knowledge transfer and the path of translational medicine. Nursing And Health Sciences, 12 (3), 284-286. http://doi.org/10.1111/j.1442-2018.2010.00546.x
Lesko, M.M., Woodford, M., White, L., O'Brien, S.J., Childs, C., & Lecky, F.E. (2010). Using Abbreviated Injury Scale (AIS) codes to classify Computed Tomography (CT) features in the Marshall System. BMC Medical Research Methodology, 10 (1), 72. http://doi.org/10.1186/1471-2288-10-72
Machin, G., & Childs, C. (2010). A systematic performance evaluation of brain and body temperature sensors using ultra-stable temperature references. Journal of Medical Engineering & Technology, 34 (3), 192-199. http://doi.org/10.3109/03091900903509156
Childs, C. (2009). Evidence-based medicine in BURNS revisited — The need for the CONSORT criteria. Burns, 35 (1), 158. http://doi.org/10.1016/j.burns.2008.05.025
Childs, C., & Machin, G. (2009). Reliability issues in human brain temperature measurement. Critical Care, 13 (4), R106. http://doi.org/10.1186/cc7943
Childs, C., Sacho, R.H., & King, A.T. (2009). Brain hyperthermia after traumatic brain injury does not reduce brain oxygen. Neurosurgery, 64 (6), E1206. http://doi.org/10.1227/01.NEU.0000346232.65178.C7
Kirk, D., Rainey, T., Vail, A., & Childs, C. (2009). Infra-red thermometry: the reliability of tympanic and temporal artery readings for predicting brain temperature after severe traumatic brain injury. Critical Care, 13 (3), R81. http://doi.org/10.1186/cc7898
Rainey, T., Lesko, M., Sacho, R., Lecky, F., & Childs, C. (2009). Predicting outcome after severe traumatic brain injury using the serum S100B biomarker: Results using a single (24h) time-point. Resuscitation, 80 (3), 341-345. http://doi.org/10.1016/j.resuscitation.2008.11.021
Childs, C. (2008). Human brain temperature: regulation, measurement and relationship with cerebral trauma : Part 1. British Journal of Neurosurgery, 22 (4), 486-496. http://doi.org/10.1080/02688690802245541
Sacho, R.H., & Childs, C. (2008). The significance of altered temperature after traumatic brain injury : an analysis of investigations in experimental and human studies : Part 2. British Journal of Neurosurgery, 22 (4), 497-507. http://doi.org/10.1080/02688690802245558
Childs, C., Jones, A.K.P., & Tyrrell, P.J. (2008). Long-term temperature-related morbidity after brain damage: survivor-reported experiences. Brain Injury, 22 (7-8), 603-609. http://doi.org/10.1080/02699050802189719
Kauppinen, R.A., Vidyasagar, R., Childs, C., Balanos, G.M., & Hiltunen, Y. (2008). Assessment of human brain temperature by 1H MRS during visual stimulation and hypercapnia. NMR in Biomedicine, 21 (4), 388-395. http://doi.org/10.1002/nbm.1204
Khojasteh, V.J., Edwards-Jones, V., Childs, C., & Foster, H.A. (2007). Prevalence of toxin producing strains of Staphylococcus aureus in a pediatric burns unit. Burns, 33 (3), 334-340. http://doi.org/10.1016/j.burns.2006.07.009
Leach, P., Childs, C., Evans, J., Johnston, N., Protheroe, R., & King, A. (2007). Transfer times for patients with extradural and subdural haematomas to neurosurgery in Greater Manchester. British Journal of Neurosurgery, 21 (1), 11-15. http://doi.org/10.1080/02688690701210562
Childs, C., Hiltunen, Y., Vidyasagar, R., & Kauppinen, R.A. (2007). Determination of regional brain temperature using proton magnetic resonance spectroscopy to assess brain–body temperature differences in healthy human subjects. Magnetic Resonance in Medicine, 57 (1), 59-66. http://doi.org/10.1002/mrm.21100
Childs, C., Vail, A., Leach, P., Rainey, T., Protheroe, R., & King, A. (2006). Brain temperature and outcome after severe traumatic brain injury. Neurocritical Care, 5 (1), 10-14. http://doi.org/10.1385/NCC:5:1:10
Johnston, N.J., King, A.T., Protheroe, R., & Childs, C. (2006). Body temperature management after severe traumatic brain injury: methods and protocols used in the United Kingdom and Ireland. Resuscitation, 70 (2), 254-262. http://doi.org/10.1016/j.resuscitation.2006.02.010
Childs, C., Vail, A., Protheroe, R., King, A.T., & Dark, P.M. (2005). Differences between brain and rectal temperatures during routine critical care of patients with severe traumatic brain injury. Anaesthesia, 60 (8), 759-765. http://doi.org/10.1111/j.1365-2044.2005.04193.x
Soop, M., Duxbury, H., Agwunobi, A.O., Gibson, J.M., Hopkins, S.J., Childs, C., ... Carlson, G.L. (2002). Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans. American journal of physiology. Endocrinology and metabolism, 282 (6), E1276-85. http://doi.org/10.1152/ajpendo.00535.2001
Childs, C., Renshaw, A., Dunn, K.W., & Davenport, P.J. (2001). The acute febrile response to burn injury in children may be modified by the type of intravenous fluid used during resuscitation — observations using fresh frozen plasma (FFP) or Hartmann's solution. Burns, 27 (4), 386-388. http://doi.org/10.1016/S0305-4179(00)00120-0
Renshaw, A., & Childs, C. (2000). The significance of peripheral skin temperature measurement during the acute phase of burn injury : an illustrative case report. Burns, 26 (8), 750-753. http://doi.org/10.1016/S0305-4179(00)00047-4
Edwards-Jones, V., Dawson, M.M., & Childs, C. (2000). A survey into toxic shock syndrome (TSS) in UK burns units. Burns, 26 (4), 323-333. http://doi.org/10.1016/S0305-4179(99)00142-4
Childs, C., Harrison, R., & Hodkinson, C. (1999). Tympanic membrane temperature as a measure of core temperature. Archives of Disease in Childhood, 80 (3), 262-266. http://doi.org/10.1136/adc.80.3.262
Childs, C., Goldring, S., Tann, W., & Hillier, V.F. (1998). Suprasternal Doppler ultrasound for assessment of stroke distance. Archives of Disease in Childhood, 79 (3), 251-255. http://doi.org/10.1136/adc.79.3.251
Childs, C. (1998). Is there an evidence-based practice for burns? Burns, 24 (1), 29-33. http://doi.org/10.1016/S0305-4179(97)00089-2
Childs, C. (1998). The European directory of Burns Research. Burns, 24 (1), 25-28. http://doi.org/10.1016/S0305-4179(97)00088-0
Edwards-Jones, V., Childs, C., & Foster, H.A. (1996). A comparison of phenotypic properties of Staphylococcus aureus isolated from burned children and other patient groups. Burns, 22 (5), 384-9. http://doi.org/10.1016/0305-4179(95)00175-1
Wright, I.P., Griffiths, M., & Childs, C. (1995). A microprocessor based photoplethysmograph for use in clinical practice. Anaesthesia, 50 (10), 875-878. http://doi.org/10.1111/j.1365-2044.1995.tb05855.x
Jenney, M.E., Childs, C., Mabin, D., Beswick, M.V., & David, T.J. (1995). Oxygen consumption during sleep in atopic dermatitis. Archives of Disease in Childhood, 72 (2), 144-146. doi:10.1136/adc.72.2.144
Childs, C., Edwards-Jones, V., Heathcote, D.M., Dawson, M., & Davenport, P.J. (1994). Patterns of Staphylococcus aureus colonization, toxin production, immunity and illness in burned children. Burns, 20 (6), 514-521. http://doi.org/10.1016/0305-4179(94)90011-6
Childs, C. (1994). Studies in children provide a model to re-examine the metabolic response to burn injury in patients treated by contemporary burn protocols. Burns, 20 (4), 291-300. http://doi.org/10.1016/0305-4179(94)90055-8
Childs, C., & Little, R.A. (1994). Acute changes in oxygen consumption and body temperature after burn injury. Archives of Disease in Childhood, 71 (1), 31-4. http://doi.org/10.1136/adc.71.1.31
Childs, C. (1993). Metabolic rate at rest and during sleep in a thermoneutral environment. Archives of disease in childhood, 68 (5), 658-661. http://doi.org/10.1136/adc.68.5.658
Childs, C., Stoner, H.B., & Little, R.A. (1992). Cutaneous heat loss shortly after burn injury in children. Clinical science (London, England : 1979), 83 (1), 117-126. http://doi.org/10.1042/cs0830117
McGuinness, K., & Childs, C. (1991). Development of an indirect calorimeter for use in infants and young children. Clinical Physics and Physiological Measurement, 12 (4), 343-351. http://doi.org/10.1088/0143-0815/12/4/004
Childs, C., Hall, T., Davenport, P.J., & Little, R.A. (1990). Dietary intake and changes in body weight in burned children. Burns, 16 (6), 418-422. http://doi.org/10.1016/0305-4179(90)90069-9
Childs, C., Heath, D.F., Little, R.A., & Brotherston, M. (1990). Glucose metabolism in children during the first day after burn injury. Archives of emergency medicine, 7 (3), 135-147. http://doi.org/10.1136/emj.7.3.135
Bianchi, A., Bruce, J., Cooper, A.L., Childs, C., Kohli, M., Morris, I.D., ... Rothwell, N.J. (1989). Increased brown adipose tissue activity in children with malignant disease. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, 21 (11), 640-641. http://doi.org/10.1055/s-2007-1009308
Childs, C., & Little, R.A. (1988). Acetaminophen (paracetamol) in the management of burned children with fever. Burns, 14 (5), 343-348. http://doi.org/10.1016/0305-4179(88)90001-0
Childs, C. (1988). Fever in burned children. Burns, 14 (1), 1-6. http://doi.org/10.1016/S0305-4179(98)90033-X
Childs, C. (1982). The management of clinical specialities. 9. A regional paediatric burns unit. Nursing focus, 4 (4), 6-7.
Conference papers
Kirk, C., & Childs, C. (2023). A case study of automated pupillometry changes over a 48-hour period following mixed martial arts sparring (Oral presentation and abstract). In BASES Conference 2023, Coventry, 16 November 2023 - 17 November 2023.
Kirk, C., Maden-Wilkinson, T., & Childs, C. (2023). Pilot data of the effects of mixed martial arts sparring on autonomic brain function (Oral presentation and abstract). In ECSS Annual Congress 2023, Paris, 4 July 2023 - 7 July 2023.
Kirk, C., Maden-Wilkinson, T., & Childs, C. (2023). Pilot pupillometry data examining the effects of mixed martial arts sparring on autonomic brain function (Poster and abstract). In ACSM Annual Meeting and World Congress 2023, Denver, 30 May 2023 - 2 June 2023.
Roscoe, S., Skinner, E., Allen, S., Childs, C., Weekes, E., McDermott, C., & Stavroulakis, T. (2022). Estimating resting energy expenditure in people living with amyotrophic lateral sclerosis [Abstract only]. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (Sup 1), 148-149. http://doi.org/10.1080/21678421.2022.2120685
Roscoe, S., Skinner, E., Allen, S., Childs, C., Weekes, E., McDermott, C., & Stavroulakis, T. (2022). Estimating resting energy expenditure in people living with amyotrophic lateral sclerosis [Abstract only]. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (Sup 1), 148-149. http://doi.org/10.1080/21678421.2022.2120685
Marshall, M., Deo, R., Childs, C., & Ali, A. (2018). Use of an automated pupillometer after acute stroke (abstract only). International Journal of Stroke, 13 (3), 49. https://journals.sagepub.com/doi/full/10.1177/1747493018801108
Gwillt, A., Homer, C., Sherriff, G., & Childs, C. (2015). Community voices in design practice: a case study of understanding older adults' clothing needs for keeping warm at home. In Britt, H., Morgan, L., & Walton, K. (Eds.) Futurescan 3: Intersecting Identities, 11 November 2015 - 12 November 2015. Creative and Print Services, Loughborough University
Childs, C., Gwilt, A., Sherriff, G., & Homer, C. Old and Cold: Challenges in the Design of PersonalisedThermal Comfort at Home. In Christer, K. (Ed.) Design 4 health: Proceedings of the 3rd European Conference on Design4Health, (pp. 1-9). Sheffield: Sheffield Hallam University
Book chapters
Childs, C. (2018). Body temperature and clinical thermometry. (pp. 467-482). Elsevier: http://doi.org/10.1016/B978-0-444-64074-1.00029-X
Selvan, A., & Childs, C. (2017). Infrared Thermal Mapping, Analysis and Interpretation in Biomedicine. In Ng, E.Y.K., & EtehadTavakol, M. (Eds.) Application of Infrared to Biomedical Sciences. (pp. 377-394). Springer: http://www.springer.com/gb/book/9789811031465
Selvan, A., & Childs, C. (2017). Infra-red thermal mapping, analysis and interpretation in biomedicine. In Ng, E.Y.K., & Etehad Tavakol, M. (Eds.) Application of Infrared to Biomedical Sciences. (pp. 377-394). Springer
Gwilt, A., Homer, C., Sherriff, G., & Childs, C. (2016). Community voices in design practice : a case study of understanding older adults’ clothing needs for keeping warm at home. In Futurescan 3 : Intersecting Identities. Creative and Print Services: http://www.ftc-online.org.uk/publications/conference/
Childs, C. (1998). The acute response to burn injury in children. In Injury in the Young. Cambridge University Press
Theses / Dissertations
Tran, W.T. (2018). Measuring Chemotherapy Response in Breast Cancer Using Optical and Ultrasound Spectroscopy. (Doctoral thesis). Supervised by Childs, C., Probst, H., & Czarnota, G.
Other publications
Cronin De Chavez, A., Childs, C., Kelly, S., Tod, A., & Burke, D. (2013). Hypothermia and the assessment of sick children. BMJ Publishing Group: http://doi.org/10.1136/bmj.f4220
Other activities
Recent Awards
2018 Shortlisted. Times Higher Education (THE) Research Project of the Year in STEM category
2018 Winner: Innovation in Surgical Site Infection
Journal of Wound Care, Banking Hall, London, March
Journal of Wound Care International Awards
2016 JWC Award winners announced: Professor Charmaine Childs has received second place in the category of Innovation in Wound Care at the recent World Union of Wound Healing Societies, held in Florence, September 2016. This prize was in recognition of Professor Child’s contribution from extending the boundaries of wound care practice to setting up new services that improve patient care, health-care professionals and researchers are developing innovative services in wound care. This award was open to individuals or teams who had demonstrated an innovative, novel approach to an existing challenge in wound care.
Further information can be found at the JWC Awards website.
Journal of Wound Care International Awards
First Prize - BEST CLINICAL RESEARCH AWARD
Banking Hall Award Ceremony, London.
March 2016
Journal of Wound Care International Awards
Third Prize- INNOVATION AWARD
Banking Hall Award Ceremony, London.
TRAM Fellowship: Brain Injury Research
2008 - Director of Operations and Executive member, South-Yorkshire Institute for Innovation and Research in Childs Health (siirch)
Steering Committee:
South Yorkshire Neuro and Professional Practice Symposia (SYNAPPS)
Peer Review
Invited Scientific Advisor: National Institute for Health Research UK: Health Technology Assessment Programme, Quality Assurance Process
Invited Expert Grant Review: Medical Research Council (MRC)/Wellcome Trust Global Health Trials Scheme
Member, Editorial Board: Scientifica
Member, Editorial Board: Frontiers in Neurotrauma
Member, Editorial Board: Nursing and Health Sciences
Editorial Board: Open Critical Care Medicine
Postgraduate supervision
Multiparametric monitoring of breast tumour response to neoadjuvant chemotherapy using quantitative ultrasound and diffuse optical imaging. Director of Studies
Role of retinal imaging as a biomarker for concussion and mild traumatic brain injury in contact sports.
Director of StudiesBiomarkers and prognostic value in predicting incidence of delirium in elderly ICU patients
Primary Supervisor, National University of Singapore
Constipation in Patients with Stroke: Incidence, Associated Risk Factors and Management at a Tertiary Hospital in Singapore :
National University of Singapore, Primary Supervisor
Longitudinal Analysis of Physiological Data from Critically Ill Patients”.
University of Manchester, UK Co-supervisor
Emergency Medicine Training Fellow. Prognostic models of traumatic brain injury: Models of Mortality Probability in Severe Traumatic Brain Injury.
University of Manchester, UK Co-supervisor
Cerebral and Systemic Responses to Whole body cooling in patients with traumatic brain injury
University of Manchester UK, Primary supervisor
Brain temperature, inflammation and Outcome after Severe Traumatic Brain injury
University of Manchester, UK Primary supervisorMedia
Charmaine is Professor of Clinical Science and is an expert in critical illness and human trauma, specifically paediatric burn injuries and traumatic brain injury in adults.
Professor Childs is undertaking innovative research in a number of fields, including using infra-red thermal imaging for wound assessment after surgery and retinal imaging after mild brain injury. Charmaine is also an executive member and director of operations for South Yorkshire Institute for Innovation and Research in Child Health.
Science