Millar, J., Gibbons, L., Costa, C., Schneider, E., von Gerichten, J., Bailey, M.J., ... Cole, L. (2023). Multimodal imaging of metals in a retinal degeneration model to inform on ocular disease. Analytica, 4 (3), 264-279. http://doi.org/10.3390/analytica4030021

Russo, C., Wyld, L., Da Costa Aubreu, M., Bury, C.S., Heaton, C., Cole, L.M., & Francese, S. (2023). Non-invasive screening of breast cancer from fingertip smears—a proof of concept study. Scientific Reports, 13 (1). http://doi.org/10.1038/s41598-023-29036-7

Clench, M.R., & Cole, L.M. (2023). Perspective: Mass Spectrometry Imaging - The Next 5 Years. Methods in molecular biology (Clifton, N.J.), 2688, 203-210. http://doi.org/10.1007/978-1-0716-3319-9_17

Cole, L.M. (2023). Preface. Methods in Molecular Biology, 2688, v.

Millar, J., Ozaki, E., Campbell, S., Duckett, C., Doyle, S., & Cole, L. (2022). Multiomic Mass Spectrometry Imaging to Advance Future Pathological Understanding of Ocular Disease. Metabolites, 12 (12). http://doi.org/10.3390/metabo12121239

Kennedy, K., Gannicliffe, C., Cole, L., Sealey, M., & Francese, S. (2022). In depth investigation of the capabilities and limitations of combined proteomic-MALDI MS based approach for the forensic detection of blood. Science & Justice, 62 (5), 602-609. http://doi.org/10.1016/j.scijus.2022.09.001

Kennedy, K., Cole, L., Witt, M., Sealey, M., & Francese, S. (2022). Forensic discrimination of differentially sourced animal blood using a bottom-Up proteomics based MALDI MS approach. Molecules, 27 (7). http://doi.org/10.3390/molecules27072039

Bury, C.S., Heaton, C., Cole, L., McColm, R., & Francese, S. (2022). Exploring the problem of determining human age from fingermarks using MALDI MS-machine learning combined approaches. Analytical Methods. http://doi.org/10.1039/d1ay02002a

Voloaca, O.M., Clench, M., Koellensperger, G., Cole, L., Haywood-Small, S., & Theiner, S. (2022). Elemental Mapping of Human Malignant Mesothelioma Tissue Samples Using High-Speed LA-ICP-TOFMS Imaging. Analytical Chemistry, 94, 2597-2606. http://doi.org/10.1021/acs.analchem.1c04857

Cole, L.M., Handley, J., Claude, E., Duckett, C.J., Mudhar, H.S., Sisley, K., & Clench, M.R. (2021). Multi-Modal Mass Spectrometric Imaging of Uveal Melanoma. Metabolites, 11 (8). http://doi.org/10.3390/metabo11080560

Flint, L.E., Hamm, G., Ready, J.D., Ling, S., Duckett, C.J., Cross, N.A., ... Clench, M.R. (2021). Comparison of Osteosarcoma Aggregated Tumour Models with Human Tissue by Multimodal Mass Spectrometry Imaging. Metabolites, 11 (8). http://doi.org/10.3390/metabo11080506

Heaton, C., Witt, M., Cole, L., Eyre, J., Tazzyman, S., McColm, R., & Francese, S. (2021). Detection and mapping of haemoglobin variants in blood fingermarks by MALDI MS for suspect "profiling". Analyst. http://doi.org/10.1039/d1an00578b

Kennedy, K., Benjat, R., Heaton, C., Herman, Y., Oz, C., Elad, M.L., ... Francese, S. (2021). "MALDI-CSI": A proposed method for the tandem detection of human blood and DNA typing from enhanced fingermarks. Forensic Science International. http://doi.org/10.1016/j.forsciint.2021.110774

Spencer, C.E., Flint, L.E., Duckett, C., Cole, L., Cross, N., Smith, D., & Clench, M. (2021). Role of MALDI-MSI in combination with 3D tissue models for early stage efficacy and safety testing of drugs and toxicants. Expert Review of Proteomics, 17 (11-12), 827-841. http://doi.org/10.1080/14789450.2021.1876568

Russo, C., Heaton, C., Flint, L., Voloaca, O., Haywood-Small, S., Clench, M., ... Cole, L. (2020). Emerging applications in mass spectrometry imaging; enablers and roadblocks. Journal of Spectral Imaging, 9, 1-21. http://doi.org/10.1255/jsi.2020.a13

Kennedy, K., Heaton, C., Langenburg, G., Cole, L., Clark, T., Clench, M.R., ... Francese, S. (2020). Pre-validation of a MALDI MS proteomics-based method for the reliable detection of blood and blood provenance. Scientific Reports, 10 (1), 17087. http://doi.org/10.1038/s41598-020-74253-z

Little, L.D., Carolan, V.A., Allen, K.E., Cole, L.M., & Haywood-Small, S.L. (2020). Headspace analysis of mesothelioma cell lines differentiates biphasic and epithelioid sub-types. Journal of Breath Research, 14 (4), 046011. http://doi.org/10.1088/1752-7163/abaaff

Pousinis, P., Ramos, I.R., Woodroofe, M.N., & Cole, L.M. (2020). Lipidomic UPLC-MS/MS Profiles of Normal-Appearing White Matter Differentiate Primary and Secondary Progressive Multiple Sclerosis. Metabolites, 10 (9), e366. http://doi.org/10.3390/metabo10090366

Heaton, C., Bury, C., Patel, E., Bradshaw, R., Wulfert, F., Heeren, R., ... Francese, S. (2020). Investigating sex determination through MALDI MS analysis of peptides and proteins in natural fingermarks through comprehensive statistical modelling. Forensic Chemistry, 20 (100271), 1-12. http://doi.org/10.1016/j.forc.2020.100271

Voloaca, O.M., Greenhalgh, C.J., Cole, L., Clench, M.R., Managh, A.J., & Haywood-Small, S. (2020). Laser ablation inductively coupled plasma mass spectrometry as a novel clinical imaging tool to detect asbestos fibres in malignant mesothelioma. Rapid Communications in Mass Spectrometry, 34 (21), e8906. http://doi.org/10.1002/rcm.8906

Flint, L.E., Hamm, G., Ready, J.D., Ling, S., Duckett, C.J., Cross, N.A., ... Clench, M.R. (2020). Characterization of an Aggregated Three-Dimensional Cell Culture Model by Multimodal Mass Spectrometry Imaging. Analytical Chemistry. http://doi.org/10.1021/acs.analchem.0c02389

Greenhalgh, C.J., Voloaca, O.M., Shaw, P., Donard, A., Cole, L.M., Clench, M.R., ... Haywood-Small, S.L. (2020). Needles in haystacks: using fast-response LA chambers and ICP-TOF-MS to identify asbestos fibres in malignant mesothelioma models. Journal of Analytical Atomic Spectrometry. http://doi.org/10.1039/d0ja00268b

Palubeckaitė, I., Crooks, L., Smith, D., Cole, L., Bram, H., Le Maitre, C., ... Cross, N.A. (2019). Mass spectrometry imaging of endogenous metabolites in response to doxorubicin in a novel 3D osteosarcoma cell culture model. Journal of Mass Spectrometry. http://doi.org/10.1002/jms.4461

Cole, L., Clench, M., & Francese, S. (2019). Sample treatment for tissue proteomics in cancer, toxicology, and forensics. Adv Exp Med Biol, 1073 (1073), 77-123. http://doi.org/10.1007/978-3-030-12298-0_4

Wojakowska, A., Cole, L., Chekan, M., Bednarczyk, K., Maksymiak, M., Oczko-Wojciechowska, M., ... Widlak, P. (2018). Discrimination of papillary thyroid cancer from non-cancerous thyroid tissue based on lipid profiling by mass spectrometry imaging. Endokrynologia Polska, 69 (1), 2-8. http://doi.org/10.5603/EP.a2018.0003

Selvan, A., Cole, L., Spackman, L., & Wright, C. (2017). Hierarchical Cluster Analysis to Aid Diagnostic Image DataVisualization of MS and Other Medical Imaging Modalities. .

Selvan, A., Cole, L., Spackman, L., & Wright, C. (2017). Hierarchical Cluster Analysis to Aid Diagnostic Image DataVisualization of MS and Other Medical Imaging Modalities. .

Harvey, A., Day, R., Cole, L.M., Bartlett, M., Warwick, J., Bojar, R., ... Clench, M.R. (2016). MALDI-MSI for the analysis of a 3D tissue-engineered psoriatic skin model. Proteomics, 16 (11-12), 1718-1725. http://doi.org/10.1002/pmic.201600036

Patel, E., Cole, L.M., Bradshaw, R., Batubara, A., Mitchell, C.A., Francese, S., & Clench, M. (2015). MALDI-MS imaging for the study of tissue pharmacodynamics and toxicodynamics. Bioanalysis, 7 (1), 91-101. http://doi.org/10.4155/bio.14.280

Cole, L.M., Selvan, A.N., Partridge, R., Reed, H., Wright, C., & Clench, M.R. (2015). Communication of medical images to diverse audiences using multimodal imaging. Advanced Structural and Chemical Imaging, 1 (1). http://doi.org/10.1186/s40679-015-0012-8

Cole, L., & Clench, M. (2015). Mass spectrometry imaging for the proteomic study of clinical tissue. PROTEOMICS - Clinical Applications, 9 (3-4), 335-341. http://doi.org/10.1002/prca.201400103

Cole, L.M., & Clench, M.R. (2015). Mass spectrometry imaging tools in oncology. Biomarkers in medicine, 9 (9), 863-868. http://doi.org/10.2217/bmm.15.61

Cole, L., Bluff, J.E., Carolan, V., Paley, M.N., Tozer, G.M., & Clench, M. (2014). MALDI-MSI and label-free LC-ESI-MS/MS shotgun proteomics to investigate protein induction in a murine fibrosarcoma model following treatment with a vascular disrupting agent. Proteomics, 14 (7-8), 890-903. http://doi.org/10.1002/pmic.201300429

Cole, L.M., Mahmoud, K., Haywood-Small, S., Tozer, G.M., Smith, D.P., & Clench, M.R. (2013). Recombinant "IMS TAG" proteins - A new method for validating bottom-up matrix-assisted laser desorption/ionisation ion mobility separation mass spectrometry imaging. Rapid Communications in Mass Spectrometry, 27 (21), 2355-2362. http://doi.org/10.1002/rcm.6693

Mahmoud, K., Cole, L., Newton, J., Mohamed, S., Al-Enazi, M., Qirke, P., & Clench, M. (2013). Detection of the epidermal growth factor receptor, amphiregulin and epiregulin in formalin-fixed paraffin-embedded human placenta tissue by matrix-assisted laser desorption/ionization mass spectrometry imaging. European Journal of Mass Spectrometry, 19 (1), 17-28. http://doi.org/10.1255/ejms.1212

Trim, P.J., Djidja, M.-.C., Muharib, T., Cole, L.M., Flinders, B., Carolan, V., ... Clench, M. (2012). Instrumentation and software for mass spectrometry imaging -making the most of what you've got. Journal of Proteomics, 75 (16), 4931-4940.

Cole, L., Djidja, M.-.C., Bluff, J., Claude, E., Carolan, V., Paley, M., ... Clench, M. (2011). Investigation of protein induction in tumour vascular targeted strategies by MALDI MSI. Methods, 54 (4), 442-453. http://doi.org/10.1016/j.ymeth.2011.03.007

Trim, P.J., Djidja, M.C., Atkinson, S.J., Oakes, K., Cole, L.M., Anderson, D.M.G., ... Clench, M.R. (2010). Introduction of a 20 kHz Nd:YVO4 laser into a hybrid quadrupole time-of-flight mass spectrometer for MALDI-MS imaging. Analytical and Bioanalytical Chemistry, 397 (8), 3409-3419. http://doi.org/10.1007/s00216-010-3874-6

Conference papers

Millar, J., Campbell, S., Duckett, C., Doyle, S.L., & Cole, L. (2022). Multimodal mass spectrometry imaging of key biomarkers to study age-related macular degeneration [Abstract only]. Investigative ophthalmology & visual science, 63 (7), 471. https://iovs.arvojournals.org/article.aspx?articleid=2778965

Cole, L., Selvan, A., Wright, C., Reed, H., & Clench, M. (2014). Communication of medical images to diverse audiences using multiple imaging modalities'. In BMSS Annual Meeting 2014, Alderley Park Conference Centre, Macclesfield, Cheshire, 1 April 2014 - 2 April 2014.

Books

Thickett-Cole, L., & Clench, M. (Eds.). (2023). Imaging Mass Spectrometry. Methods and Protocol. 2nd edition. New York: Humana Press. https://link.springer.com/book/10.1007/978-1-0716-3319-9

Thickett-Cole, L. (Ed.). (2017). 978-1-4939-7051-3 Published: 18 May 2017(first). Springer.

Theses / Dissertations

Guarnerio, S. (2023). A multi-model study of extracellular vesicles in bowel cancer invasion and metastasis. (Doctoral thesis). Supervised by Peake, N., Le Maitre, C., & Cole, L. http://doi.org/10.7190/shu-thesis-00581

Little, L.D. (2022). Volatile organic compounds as breathomicviomarkers of malignant mesothelioma. (Doctoral thesis). Supervised by Haywood-Small, S., Carolan, V., Allen, L., & Cole, L. http://doi.org/10.7190/shu-thesis-00495

Heaton, C.E.G. (2022). Human identification through advanced forensic mass spectrometry of blood and fingermarks. (Doctoral thesis). Supervised by Francese, S., Cole, L., & McColm, R. http://doi.org/10.7190/shu-thesis-00500

Flint, L.E. (2021). Imaging Three-Dimensional Cell-Culture Models for Pre-Clinical Biopharmaceutical Testing. (Doctoral thesis). Supervised by Clench, M., Cross, N., Cole, L., & Smith, D. http://doi.org/10.7190/shu-thesis-00406

Posters

Wright, C., Reed, H., Partridge, R., Cole, L., Selvan, A., & Clench, M. (2014). Communication of multi-modal imaging:MRI, MSI, and histology. Presented at: BCISMRM, Edinburgh, 2014