My research is on the effects of low-level carbon monoxide on physiology and disease development. Carbon monoxide is a poisonous gas that most of us breathe in every day through air pollution. Worldwide, the World Health Organisation estimates that 4.2 million deaths per year occur due to air pollution, and we know that carbon monoxide air pollution is linked with increased incidence of vascular diseases, such as stroke and vascular dementia. I have shown that even small amounts of the gas have significant impact on cerebral blood flow and cerebrovascular function. However, we do not yet know precisely how low-level carbon monoxide exposure affects vascular health and contributes to pathophysiology. Nor do we know how much carbon monoxide is safe to breathe over time. In my research I aim to address this using a combination of imaging and physiological/biological and behavioural data.
This research naturally lends itself to undergraduate and postgraduate research projects.