Biomolecular Sciences Research Centre

Interdisciplinary bioscience and chemistry addressing complex challenges in health, disease, biotechnology, forensic science and beyond.

BMRC unites researchers, technical specialists, and doctoral candidates in bioscience, chemistry, and advanced analytical science. We integrate fundamental discoveries with applied research, collaborating with academic, public sector, and industry partners to create new knowledge, technologies, and practical solutions.

36 researchers | 26 doctoral researchers | 6 research areas | Specialist analytical and biological facilities Designated commercial unit

Complex scientific challenges rarely sit within a single discipline. BMRC brings together biological, chemical, analytical and computational expertise to explore questions across traditional boundaries from molecular mechanisms of disease and advanced cell models to microbial biotechnology, environmental challenges and new approaches to chemical and molecular analysis.

Mass Spectrometry Imagine Group - Figure mark image

Revealing new molecular evidence
Advanced mass spectrometry imaging and analytical approaches are being applied across areas including forensic science, drug delivery and disease research. 

Cancer Research Group

Understanding disease and therapeutic response
BMRC research spans molecular and cellular cancer mechanisms, treatment resistance, advanced cell and tissue models, stress pathways, immunology and translational interventions.

Health and disease research group

Harnessing biology and chemistry
Research ranges from microbial biotechnology, antimicrobial resistance and bioremediation to synthesis, catalysis, materials chemistry and analytical science.


Our Research

Our researchers work across six connected areas spanning fundamental discovery, applied bioscience and chemistry, advanced analytical technologies and translational research.

Research supported by BBSRC · MRC · EPSRC · Innovate UK · Dstl · Paxman · CO Research trust
Selected Collaborators Paxman · West Yorkshire Police · Waters · AstraZeneca · Croda

We work with businesses and organisations locally, nationally and internationally, providing access to specialist expertise and advanced research facilities. Our dedicated commercial team supports projects ranging from one-off analysis and technical problem-solving to contract research, consultancy and long-term R&D partnerships. Explore our commercial services and ways to work with us

Not sure where to start? Tell us about your research question or technical challenge, and we'll connect you with the appropriate expertise.

 

Our Research

Accessibility of Science

Understanding how people engage with bioscience and chemistry, and developing more inclusive approaches to science education and public engagement. 

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Bioanalytical science

Developing and applying advanced mass spectrometry and molecular imaging approaches across biological, pharmaceutical and forensic research. 

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Cancer research

Investigating cancer mechanisms, therapeutic response and translational interventions, alongside bioinformatics and data-driven approaches. 

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Chemistry

Developing chemical, analytical and materials-based approaches for biomedical, environmental and industrial challenges. 

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Health disease and molecular biosciences

Understanding disease and human health through advanced cell models, molecular signalling, immunology, environmental physiology and related approaches. 

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Microbiology and biotechnology

Using microbial systems to address challenges including antimicrobial resistance, infection, environmental contamination and sustainable biotechnology. 

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Research Impact 

A photo point at a nature-based solution in Limb Brook Valley ©Sheffield & Rotherham Wildlife Trust

Citizen scientists

The current citizen-science project has good evidence: over two years, the public supplied more than 4,500 photographs to help monitor nature-based flood interventions, and the resulting research has informed how partners such as the Environment Agency and Sheffield & Rotherham Wildlife Trust manage and extend the approach.

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molecular images of fingermarks

Molecular fingerprinting

BMRC-led research in molecular fingerprinting has contributed to an AI-powered system using MALDI mass spectrometry imaging to recover and analyse molecular fingermark images. The technology has been trialled by West Yorkshire Police following collaboration involving Sheffield Hallam, the University of Bradford, Molecular Discovery, Waters Corporation and regional forensic services.

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Healthcare award

A longstanding Sheffield Hallam partnership with Paxman has used cell-biology research to inform technologies aimed at reducing chemotherapy-induced hair loss and other treatment side effects; the partnership was shortlisted for a Medilink North of England healthcare award in 2025.

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Developing researchers

The close proximity of academics from a range of backgrounds enables us to conduct interdisciplinary projects and innovate in new areas. Our doctoral researchers work within BMRC's multidisciplinary research community alongside academic and technical specialists. Explore our research opportunities, funding routes and doctoral programmes

A supportive and inclusive research environment

We aim to create an environment in which researchers, technical colleagues and doctoral researchers can develop, collaborate and contribute fully to our research community.

Athena Swan Silver. Recognition of our ongoing work to advance gender equality and develop an inclusive working environment. 

Bronze LEAF accreditation. Recognising our commitment to sustainable laboratory practice, including improved energy and resource efficiency, waste reduction and responsible use of laboratory materials.  

Impact Case Study Leads

Mari Herigstad

Dr Mari Herigstad

Senior Lecturer, School of Biosciences and Chemistry

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Mel Lacey 218475

Dr Mel Lacey

Associate Professor, School of Biosciences and Chemistry

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Nik Georgopoulos

Dr Nik Georgopoulos

Associate Professor, School of Biosciences and Chemistry

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Professor Tom Smith

Professor Tom Smith

Professor of Microbiology and Biotechnology

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Professor Simona Francese

Professor Simona Francese

Professor of Forensic and Bioanalytical Mass Spectrometry

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