I joined Sheffield Hallam University from the University of Cambridge, where I undertook a PhD (2008-2012) and post-doctoral research (2012-2015) with Professor Steven V. Ley CBE FRS. Prior to this, I attained my undergraduate degree at the University of Warwick (2004-2008). My current research programme is focused on the development of practical synthetic and catalytic organic transformations; in particular, sp2-sp3 and sp3-sp3 carbon-carbon bond formation.
Fundamentals of Organic Chemistry
Organic and Biological Chemistry
Advanced Organic Synthesis and Spectroscopy
Medicinal Chemistry and Drug Discovery
R.R. Merchant, D.M. Allwood, D.C. Blakemore and S.V. Ley, Regioselective preparation of saturated spirocyclic and ring-expanded fused pyrazoles, J. Org. Chem. 2014, 79, 8800-8811.
D.M. Allwood, D.L. Browne and S.V. Ley, Synthesis and use of a trifluoromethylated azomethine ylide precursor: Ethyl 1-benzyl-trans-5-(trifluoromethyl)pyrollidine-3-carboxylate, Org. Synth. 2014, 91, 162-174.
T.M. Beale, D.M. Allwood, A. Bender, P.J. Bond, J.D. Brenton, D.S. Charnock-Jones, S.V. Ley, R.M. Myers, J.W. Shearman, J. Temple, J. Unger, C.A. Watts and J. Xian, A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles, ACS Med. Chem. Lett. 2012, 3, 177-181.
BATTILOCCHIO, Claudio, FEIST, Florian, HAFNER, Andreas, SIMON, Meike, TRAN, Duc, ALLWOOD, Daniel, BLAKEMORE, David and LEY, Steven (2016). Iterative reactions of transient boronic acids enable sequential C–C bond formation. Nature Chemistry, 8 (4), 360-363.
ROUQUET, Guy, MOORE, Dianna E., SPAIN, Malcolm, ALLWOOD, Daniel, BATTILOCCHIO, Claudio, BLAKEMORE, David C., FISH, Paul V., JENKINSON, Stephen, JESSIMAN, Alan S., LEY, Steven V., MCMURRAY, Gordon and STORER, R. Ian (2015). Design, synthesis, and evaluation of tetrasubstituted pyridines as potent 5-HT2CReceptor agonists. ACS Medicinal Chemistry Letters, 6 (3), 329-333.
ALLWOOD, Daniel, BLAKEMORE, David C., BROWN, Alan D. and LEY, Steven V. (2014). Metal-free coupling of saturated heterocyclic sulfonylhydrazones with boronic acids. The Journal of Organic Chemistry, 79 (1), 328-338.
ALLWOOD, Daniel, BLAKEMORE, David C. and LEY, Steven V. (2014). Preparation of unsymmetrical ketones from tosylhydrazones and aromatic aldehydes via formyl C–H bond insertion. Organic Letters, 16 (11), 3064-3067.
Jack Slater – Synthesis of Novel Potential Antibiotics Using Visible Light Photoredox Catalysis (Oct 2017-Oct 2020)
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