Biomedical Laboratory Science

This module aims to equip you with both practical skills and theoretical knowledge of laboratory-based research and examine the important issues that make good laboratory practice. Within the programme, this module will prepare you for the semester two laboratory module and the semester three independent research project.

You’ll study topics such as:
• Fundamental practical laboratory training (including reagent preparation, accuracy and precision in performing experiments, health and safety) which will be underpinned by subject module theoretical knowledge.
• A range of course focussed laboratory methodologies and, where appropriate, other practical procedures.
• Effective communication and presentation skills development via the preparation of visual and written work in an appropriate context.
• Introduction to ethical issues and foundations of scientific integrity forming the implications of good laboratory practice.
• Understand and apply fundamental statistical methods for data analysis.
• Employability skills and career preparation (including CV development, application process).

This module will introduce you to the cellular and molecular basis of disease, providing foundational knowledge of how disruptions in normal cellular processes lead to pathological conditions, and to develop your ability to effectively communicate scientific findings in the context of disease mechanisms.

You’ll study topics such as:
• Cell Culture and Cellular Analysis
• Principles and techniques of cell culture
• Methods used to study cellular structures and functions
• Applications of cellular techniques in assessing disease states

Metabolic Pathways and Disease:
• Overview of some metabolic pathways
• Alterations in these pathways in diseases such as diabetes and cardiovascular disorders

Genetic and Molecular Mechanisms in Health and Disease:
• Gene structure and chromosome organisation
• DNA replication, transcription, translation, protein folding, and post-translational modifications
• Dysregulation of these processes in conditions such as cancer and neurodegenerative diseases

Cellular Fates and Their Regulation in Disease:
• Mechanisms of apoptosis, cell division, cancer transformation, and differentiation
• How disruptions in these regulatory controls lead to diseases such as cancer and developmental disorders

Cell Communication and Disease:
• Role of cell communication in biological processes such as tissue growth, angiogenesis, immune responses, and stem cell determination
• Impact of disrupted communication on disease states, including cancer, diabetes, and immunological disorders

Extracellular Vesicles in Cellular Communication:
• Synthesis and roles of extracellular vesicles in intercellular signalling
• Contributions of extracellular vesicles to disease progression and pathology

Cytoskeleton and Extracellular Matrix in Health and Disease:
• Functions of the cytoskeleton and extracellular matrix in cellular structure and tissue organisation
• Structural and functional alterations in these components in disease states such as fibrosis, Metastasis, and cardiovascular diseases

This module helps you develop the skills to plan and design your research project. You’ll learn how to review existing research, create a clear research proposal, and build a strong foundation for your experimental study. By the end, you’ll know how to turn research ideas into a well-structured academic project.

You’ll study topics such as:
• Conduct an independent literature review to enhance critical analysis and understanding of research topics.
• Design a structured research proposal with clear aims, ethical considerations, and safety protocols.
• Develop practical lab skills through structured experiments, including data analysis and troubleshooting.
• Understand and apply statistical methods for data analysis.
• Gain an understanding of the ethical and appropriate use of artificial intelligence in research.
• Help identify and articulate your employability skills.

Engaging with these core areas will prepare you for the demands of independent research and professional scientific practice.

This module provides an immersive research experience, enabling you to conduct a substantial, focused research project. Tailored to your specific degree programme, the project will challenge you to transform theoretical knowledge into practical scientific investigation.

You’ll study topics such as:
• Hands-on acquisition of advanced laboratory techniques and practical research skills
• In-depth critical analysis of experimental results, developing sophisticated scientific reasoning
• Preparation of a professional, article-style written research report demonstrating scholarly communication
• Development of oral scientific communication skills through project presentation.
• Active engagement with the research community, participating in collaborative research environments.
The module integrates practical research experience with critical academic skills, preparing you for advanced scientific research and professional scientific communication. By the conclusion of this project, you will have demonstrated independent research capabilities and contributed meaningful insights to your specific research field.