Molecular Microbiology

This module aims to equip you with both practical skills and theoretical knowledge of laboratory-based research and examine the important issues that make good laboratory practice. Within the programme, this module will prepare you for the semester two laboratory module and the semester three independent research project.

You’ll study topics such as:
• Fundamental practical laboratory training (including reagent preparation, accuracy and precision in performing experiments, health and safety) which will be underpinned by subject module theoretical knowledge.
• A range of course focussed laboratory methodologies and, where appropriate, other practical procedures.
• Effective communication and presentation skills development via the preparation of visual and written work in an appropriate context.
• Introduction to ethical issues and foundations of scientific integrity forming the implications of good laboratory practice.
• Understand and apply fundamental statistical methods for data analysis.
• Employability skills and career preparation (including CV development, application process).

This module explores the fundamental principles of microbiology on a molecular level that underpins both environmental and medical microbiology. How microbes sense their environment will be explored and how this information alters the microbes on the levels of the transcriptome, proteome and metabolome with be investigated. The virulence mechanisms and strategies that microorganisms apply throughout the infection cycle will be examined. Including, how the pathogen comes into contact with the host, how it establishes infection, the direct and indirect toxic effects on the host caused by the pathogen and strategies that can be employed to mitigate these effects will all be discussed. This will be supported by key knowledge surrounding microbial structure, metabolism and virulence with relevant lab classes, seminars and lectures.   

You’ll study topics such as: 

• Prokaryotic cellular physiology 
• Transcriptional control systems 
• Microbial metabolism 
• Cell signalling pathways 
• Biofilms 
• Viral physiology and pathogenesis 
• Factors affecting transmission of a pathogen from host to host, from the environment to the host or from vector to host 
• Attachment and invasion of host cells/host tissue by microorganisms 
• The secretion of toxins or other extracellular virulence factors 
• Microbial evasion of the host immunological response 
• The development and spread of antimicrobial resistance 
• The use of vaccines, antibiotics and other therapeutic approaches for the prevention and/or treatment of infection 

This module helps you develop the skills to plan and design your research project. You’ll learn how to review existing research, create a clear research proposal, and build a strong foundation for your experimental study. By the end, you’ll know how to turn research ideas into a well-structured academic project.

You’ll study topics such as:
• Conduct an independent literature review to enhance critical analysis and understanding of research topics.
• Design a structured research proposal with clear aims, ethical considerations, and safety protocols.
• Develop practical lab skills through structured experiments, including data analysis and troubleshooting.
• Understand and apply statistical methods for data analysis.
• Gain an understanding of the ethical and appropriate use of artificial intelligence in research.
• Help identify and articulate your employability skills.

Engaging with these core areas will prepare you for the demands of independent research and professional scientific practice.

This module provides an immersive research experience, enabling you to conduct a substantial, focused research project. Tailored to your specific degree programme, the project will challenge you to transform theoretical knowledge into practical scientific investigation.

You’ll study topics such as:
• Hands-on acquisition of advanced laboratory techniques and practical research skills
• In-depth critical analysis of experimental results, developing sophisticated scientific reasoning
• Preparation of a professional, article-style written research report demonstrating scholarly communication
• Development of oral scientific communication skills through project presentation.
• Active engagement with the research community, participating in collaborative research environments.
The module integrates practical research experience with critical academic skills, preparing you for advanced scientific research and professional scientific communication. By the conclusion of this project, you will have demonstrated independent research capabilities and contributed meaningful insights to your specific research field.